Protein Alignment lds and smarca2

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_073805988.1
• Gene: smarca2 / 334032
• ZFINID: ZDB-GENE-030131-5964
• Length: 1578
• Species: Danio rerio
• Alignment Length: 1166
• Identity: 238/1166 - (20%)
• Similarity: 428/1166 - (36%)
• Gaps: 354/1166 - (30%)

  Fly    44 PSSAGVVIDETQSEEEESQSSETAESEKSDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPS 108
            |:|...:....|:..:.|...:..|.:.::.|...|....|..|...|..|....|..:|  :||
Zfish   238 PASGQCLSPAMQTHTQSSGPKQWTEGQGAETSSTPQKLLISAPSGRPSPAPPLAPTGTQP--VPS 300

  Fly   109 DSEDEED---------------ELEQRALSPSTRMSITGV-RPQDLSDDD--SEIEYS------- 148
            .|...:.               :|:|:      :..:|.: :||.|...:  .|.||.
Zfish   301 TSLTSQPQPQPPAGPGQPSLIIQLQQK------QNRVTPIQKPQGLDPVELLQEREYRLQARIAH 359

  Fly   149 --DEVQEGPTEAP-------TAEAVVPRYTTQFAGNIQNDLHSTIGAA--DSEVLDDSSGSDVLI 202
              .|::..|...|       |.|....|..     |.|..|...:.|.  ....|:.:..|....
Zfish   360 RIQELENLPGSLPPDLRTKATVELKALRLL-----NFQRQLRLDVVACMRRDTTLETALNSKAYK 419

  Fly   203 LSNKET--------PIEILSSTDDDATTNKENMS--------GPPFERPSKSLSPRSSAGASVVK 251
            .|.::|        .:|.....:.:....:::..        ...|:...:|:|      ..:.|
Zfish   420 RSKRQTLREARMTEKLEKQQKIEQERKRRQKHQEYLNSILQHAKDFKEYHRSIS------GKIQK 478

  Fly   252 TSKNLSQPTIQAVLKQKTSP---AAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSD----- 308
            .||.::........:||...   ...|..|:.:||::...:::..::.::||....|..:
Zfish   479 LSKAIATWHTNTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDKRLAYLLQQTDEYVANL 543

  Fly   309 AEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISAL---------RVQQSNVPAVRVVKP- 363
            .|.::|   ||......:..|:....::| |.|.:.:.|:         ..|.|.:| |:|::.
Zfish   544 TELVYE---HKAAQAAKEKKKKRKKKKKE-AGDAEGMGAIGPDGEPIDENSQMSELP-VKVIQTE 603

  Fly   364 --------------------TLNP-----PRAPSIDT-LDWDE------LSEAVNEIKPVYTGAQ 396
                                .:||     ||:.|.:: .|::|      :|.|.:|.|.|.....
Zfish   604 TGKVLQGTDAPKSSQLEAWLEMNPGYEVAPRSDSEESGSDFEEEDDEEVVSRAESEEKKVIDPNS 668

  Fly   397 GMATFNNQKALTLESLKD---------------------LHVSLEDLPGPEVLAEDPVGLKVSLM 440
            ...:....|.: :||.|.                     .|..:|     .|..:....:..:|.
Zfish   669 DEVSETAAKHI-IESAKQDVDDEYSSQAGQTSSQSYYGVAHAVIE-----RVDKQSTFLINGTLK 727

  Fly   441 NHQKHALAWM-SWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDK 504
            .:|...|.|| |.....|  .|||||:||||||:..|..:......:.::
Zfish   728 QYQIQGLEWMVSLYNNNL--NGILADEMGLGKTIQTIGLITYLMEHKRLN--------------- 775

  Fly   505 NKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVES------KVS-------RQKLTVCV 556
                                |..|::.|.|.|..|..|::.      |::       |:.|...:
Zfish   776 --------------------GPYLIIVPLSTLSNWVYELDKWAPSIVKIAYKGTPSMRRSLVPQL 820

  Fly   557 HHGNNRETKGKYLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCD 621
            ..|.           :::::|||:.:.::...|:.   ::|:.:|:||.|.::||..:.:..
Zfish   821 RSGK-----------FNVLITTYEYIIKDKHILAK---IRWKYMIVDEGHRMKNHHCKLTQV--- 868

  Fly   622 LRGKY----RWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSA-GGQ--------- 672
            |...|    |..|||||:|||..:::|||.||..:.|....|:::|.:...| .|:
Zfish   869 LNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEET 933

  Fly   673 ----NRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQ 733
                .||:.:::..:|||.|.:::|     .||.|...:|     |.:|:..|.|:
Zfish   934 ILIIRRLHKVLRPFLLRRLKKEVES-----QLPEKVEYVI-----KCDMSAIQKVL--------- 979

  Fly   734 FLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMA-GSKKEVK----SHDILVLLL 793
                                            |..|..|...:. ||:|:.|    :..::..::
Zfish   980 --------------------------------YRHMQGKGILLTDGSEKDKKGKGGAKTLMNTIM 1012

  Fly   794 RLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDG 858
            :|::||.||.:...:   |||  ..:|                            ....|....|
Zfish  1013 QLKKICNHPYMFQHI---EES--FAEH----------------------------LGFPNGIISG 1044

  Fly   859 PPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDI 923
            |                        :|:|.|.|..::.:||..  ||:::.:.::..|.||::.|
Zfish  1045 P------------------------DLYRASGKFELLDRILPK--LKATNHRVLLFCQMTSLMTI 1083

  Fly   924 LRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDL 988
            |.|:........|.|:||...::|..::.:||:..:|..:.|||..|||:||||..|:.:::.|.
Zfish  1084 LEDYFGYRNFLYLRLDGTTKSEDRAMLLKKFNEEGSQYFIFLLSTRAGGLGLNLQAADTVVIFDS 1148

  Fly   989 HWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSSK 1049
            .|||..:.|||||.:|:||:..|.:.:...|::||::|......||::...|:.......|
Zfish  1149 DWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQK 1209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	184/858 (21%)
		DEXHc_TTF2	439..686	CDD:350830	65/278 (23%)
smarca2	XP_073805988.1	None