Protein Alignment lds and kis

DIOPT Version :9

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001137761.1
• Gene: kis / 33185
• FlyBaseID: FBgn0266557
• Length: 5517
• Species: Drosophila melanogaster
• Alignment Length: 1167
• Identity: 260/1167 - (22%)
• Similarity: 422/1167 - (36%)
• Gaps: 371/1167 - (31%)

  Fly     1 MSSE-NSEYYSDKEEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSS 64
            |||: |..|.:..:|||:|....|........|.......|:..|..     ||.:||.:|:
  Fly  1628 MSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQ-----DEEKSELDEA--- 1684

  Fly    65 ETAESEKSDESDNSQNSQESE--DSEDDSVRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTR 127
             |.:..:.||...::...:.:  |||:..:..||.....|....|.||:..:::
  Fly  1685 -TTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDED----------- 1737

  Fly   128 MSITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAAD---- 188
                       :.|..::|..|||.:...|:...|......|.:.:..|:.|..||:..||
  Fly  1738 -----------NKDKDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKE 1791

  Fly   189 -------SEVLDDSSGSDVLILSNKETPIEILSSTDD----DATT--NKENMSGPPFERPSKSLS 240
                   .|| |:.:..|...:|..|...|  .||||    :|||  |||::.       .:...
  Fly  1792 PETVLEKMEV-DEKANDDQSAVSKAEGSDE--KSTDDSNPEEATTEKNKESLE-------IEGEK 1846

  Fly   241 PRSSAGASVVKTS---------KNLSQP-----------------------TIQAVLKQKTSPAA 273
            .|...|...||..         :|..:|                       |.:.:||.....||
  Fly  1847 ERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAA 1911

  Fly   274 P-RRSRIKSEDQKVVSQVVYDE-------EMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKR 330
            . ||.:.|...|..:.:.:.||       |:.::.:..|...:...  |...|.|. |...:...
  Fly  1912 KIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSG--ETTKHYLV-KWKSLPYE 1973

  Fly   331 IDTLRRELAMD----EQWISALRV-QQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKP 390
            ..|...|..:|    ||::...:: |:|...:.:...|.|            |.:|     |..|
  Fly  1974 DCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPEL------------WKKL-----EKTP 2021

  Fly   391 VYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWM--SWR 453
            ||.|..                                         ||..:|...|.|:  ||.
  Fly  2022 VYKGGN-----------------------------------------SLRPYQLEGLNWLKFSWY 2045

  Fly   454 ERKLPRGGILADDMGLGKT---LTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWK 515
            .   ....||||:||||||   ||.:.||.
  Fly  2046 N---THNCILADEMGLGKTIQSLTFVHSVY----------------------------------- 2072

  Fly   516 SKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGN-------------NRETKGK 567
                :...||..||:.|.|.:..|:.|.|....   :.|.|:||:             .:...||
  Fly  2073 ----EYGIRGPFLVIAPLSTIPNWQREFEGWTD---MNVVVYHGSVTSKQMIQDYEYYYKTESGK 2130

  Fly   568 YLRD---YDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWA 629
            .|::   :::::||::::..::..|.|   ..||..::||||.::|...:....:..|..::|..
  Fly  2131 VLKEPIKFNVLITTFEMIVTDYMDLKA---FNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVL 2192

  Fly   630 LTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDN-KSAGGQNRLNLLMKSLMLRRTKAQLQS 693
            |:|||:||...::::||.||..|.|.....:.....: ::....|:|..|:|.:||||.|..::
  Fly  2193 LSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVE- 2256

  Fly   694 DGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNY----RSDANKP 754
                .||..||..:||:.|...:...|:.::                 |.:|::    .:.||.|
  Fly  2257 ----KSLAPKEETIIEVELTNIQKKYYRGIL-----------------EQNFSFLKKGTTSANIP 2300

  Fly   755 TYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGD 819
                                            :::..::.||:.|.||.|    |:|.|.|...|
  Fly  2301 --------------------------------NLMNTMMELRKCCIHPYL----LNGAEEQIQYD 2329

  Fly   820 ----HSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSN 880
                |..|.::...:|:....|:.:.|                 .|||.
  Fly  2330 FKSQHGEDPESYYKNLILSAGKMVLID-----------------KLLPK---------------- 2361

  Fly   881 PVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVK 945
                                   ||::..:.::.||....||||.|:|.........::|.|...
  Fly  2362 -----------------------LKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGN 2403

  Fly   946 NRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKN 1010
            .||:.::.::...:.:.|.||...|||:|:||..|:.:::.|..||||.:.|||.|.:|:||:|.
  Fly  2404 LRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKM 2468

  Fly  1011 VIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGA----------KVSSKLTIDDL--KGLFG 1060
            |.||:.:|.:|.|:.:......||.|...||...          |..||..|:||  ||.:|
  Fly  2469 VKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYG 2530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	SNF2_N	442..805	CDD:278600	87/388 (22%)
		DEXDc	459..634	CDD:238005	45/193 (23%)
		HELICc	885..1014	CDD:238034	38/128 (30%)
kis	NP_001137761.1	BASP1	1554..1786	CDD:283191	42/188 (22%)
		HepA	1676..2527	CDD:223627	243/1109 (22%)
		SDA1	<1693..>1854	CDD:283052	43/192 (22%)
		CHROMO	<1879..1919	CDD:237991	7/39 (18%)
		Chromo	1941..1996	CDD:278797	11/57 (19%)
		DEXDc	2048..2197	CDD:238005	45/193 (23%)
		Helicase_C	2350..2464	CDD:278689	39/169 (23%)
		RR_TM4-6	3728..>3877	CDD:283990
		BRK	4569..4613	CDD:197800

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467119
Domainoid	1	1.000	47	1.000	Domainoid score	I705
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840