Protein Alignment lds and Chd2

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_063118674.1
• Gene: Chd2 / 308738
• RGDID: 1310056
• Length: 1840
• Species: Rattus norvegicus
• Alignment Length: 1142
• Identity: 247/1142 - (21%)
• Similarity: 433/1142 - (37%)
• Gaps: 327/1142 - (28%)

  Fly     2 SSENSEYYSDKEEDSVVNNSS-LGRSRKSSRLSKSSRL------------------SKSSRPSSA 47
            |||:||..|:.|.:|..:.|. :....|....||..|:                  |..||...:
  Rat    69 SSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPS 133

  Fly    48 GVVIDETQSEEEESQSS--------ETAESEKSDESDNSQNSQESEDSEDD-----SVRPSARNT 99
            ...|.|..|...||.|.        :..|..|.|.|::.|....|.:||.:     :.||..|.|
  Rat   134 RFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQDPSEDDQEQGSSAESEAEQKKVKARRPIPRRT 198

  Fly   100 KRKP--------------LGIPSDSEDEEDELEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDE 150
            ..||              ....||.:|::||..:|   .:.|.:...|..::  |||.|.:..|.
  Rat   199 VPKPQVKKQPKIQRGKRKKQESSDDDDDDDEAPKR---QTRRRAAKNVSYKE--DDDFETDSDDL 258

  Fly   151 VQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPIEILSS 215
            ::      .|.|.|          :.|.|...||    .:|||...|..              .:
  Rat   259 IE------MTGEGV----------DEQQDNSETI----EKVLDSRLGKK--------------GA 289

  Fly   216 TDDDATTNKENMSGPPFERPSKSLSPRSSAGA--------------SVVKTSKNLSQPTIQAVLK 266
            |....|......:|.    ||.........|.              |..::.::|.|..::.:.|
  Rat   290 TGASTTVYAVEANGD----PSGDFDTEREEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKK 350

  Fly   267 QKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRI 331
            .:...        |.||:       ..:.:.|::.:.|:..:.:   :::|.:| :|..||::|:
  Rat   351 LENFK--------KKEDE-------IKQWLGKVSPEDVEYFNCQ---QELASEL-NKQYQIVERV 396

  Fly   332 DTLRRELAMDEQWISALRVQQSNVPA-VRVVKPTLNPPRAPSIDTLDWDELS---EAVNEIKPVY 392
            ..::         .|...:.|::.|| .|...|:..|........|.:.|.|   ||:.. |...
  Rat   397 IAVK---------TSKSALGQTDFPAHSRKPAPSNEPEYLCKWMGLPYSECSWEDEALIG-KKFQ 451

  Fly   393 TGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPV---GLKVSLMNHQKHALAWM--SW 452
            :......:.||.|.:.....|    :|:..|....|.:.|.   |..:.|.::|...|.|:  ||
  Rat   452 SCIDSFHSRNNSKTIPTRECK----ALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLAHSW 512

  Fly   453 RERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSK 517
            .:   ....||||:||||||:..||.:....:..::
  Rat   513 CK---SNSVILADEMGLGKTIQTISFLSYLFHQHQL----------------------------- 545

  Fly   518 GRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGN--NRETKGKYLRDYD------- 573
                  .|..|:|.|.|.|..|:.|.|  :...::.|.|:.|:  :|.|    :|:|:
  Rat   546 ------YGPFLIVVPLSTLTSWQREFE--IWAPEVNVVVYIGDLMSRNT----IREYEWIHSQTK 598

  Fly   574 -----IVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGT 633
                 .::|||:|:.::...|.:   :.|..:.:||||.::|..|.....:.|.:..:|..:|||
  Rat   599 RLKFNALITTYEILLKDKTVLGS---INWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGT 660

  Fly   634 PIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQN---RLNLLMKSLMLRRTKAQLQSDG 695
            |:||...::::||.|:....|:   .|:.:.::...|.:|   .|:.:::..:|||.|..::
  Rat   661 PLQNSLKELWSLLHFIMPEKFE---FWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVE--- 719

  Fly   696 KLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIK 760
              .|||.|..:::.:.:...:...|:.::|.                   ||::.|        |
  Rat   720 --KSLPAKVEQILRVEMSALQKQYYKWILTR-------------------NYKALA--------K 755

  Fly   761 DPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSD 825
            ...|:                   :...|.:::.|::.|.|..||.|..|.|.
  Rat   756 GTRGS-------------------TSGFLNIVMELKKCCNHCYLIRAPEDSER------------ 789

  Fly   826 TPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSS 890
                            :|..:..||                                  |.|.|.
  Rat   790 ----------------ETGQEVLQS----------------------------------LIRSSG 804

  Fly   891 KINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFN 955
            |:.::.::|  :.|:...::.::.||...:||||.::|:........|:|:|..:.|:..::.||
  Rat   805 KLILLDKLL--TRLRERGNRVLIFSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFN 867

  Fly   956 DRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVD 1020
            ...::....|||..|||:|:||..|:.:::.|..||||.:.|||.|.:|:||||.|.||:.:...
  Rat   868 ADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKG 932

  Fly  1021 TVEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKG 1057
            |||:.|.....||:.|...|:.....:.:..:::..|
  Rat   933 TVEEEIIERAKKKMVLDHLVIQRMDTTGRTVLENNSG 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	172/779 (22%)
		DEXHc_TTF2	439..686	CDD:350830	63/265 (24%)
Chd2	XP_063118674.1	None