Protein Alignment lds and Chd9

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_038953982.1
• Gene: Chd9 / 307726
• RGDID: 1306795
• Length: 2883
• Species: Rattus norvegicus
• Alignment Length: 1147
• Identity: 245/1147 - (21%)
• Similarity: 423/1147 - (36%)
• Gaps: 371/1147 - (32%)

  Fly    26 SRKSSRLSKSSRLSKSSRPSSAGVVIDETQSE-EEESQSSETAESEKSDESDNSQNSQESEDSED 89
            ||....|.:....||.|..|.....:..||.. ..|.:..:.||||...|..|...|:....:::
  Rat   474 SRSHLCLQRQPPSSKKSDGSGTYSRLQNTQVRVMSEKKPRKKAESESKQEKANRIISEAIARAKE 538

  Fly    90 DSVRPSARNTKR--KPLGIPSDSED-EEDELEQRALSPSTRMSITGVRPQDLSD----------D 141
                ...||..|  .|...||.|.| :|::..||..|          :|:|..:          :
  Rat   539 ----RGERNIPRVMSPENFPSSSVDGKEEKRAQRVKS----------KPKDRDNRKPKACSKLKE 589

  Fly   142 DSEI---------------EYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEV 191
            .::|               |.|||:.:       ||. :|::|.:       :.||....::.:|
  Rat   590 KTKIGKLIITLGKNHKRRSESSDELSD-------AEQ-MPQHTFK-------EQHSQKRRSNRQV 639

  Fly   192 -----LDDSSGSDVLILSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVK 251
                 .:|:.|        ::...|:..|     ...|...:.||.|:|
  Rat   640 KRKKYAEDAEG--------RQCEEEVRGS-----LKVKRTSAPPPGEQP---------------- 675

  Fly   252 TSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKV 316
                     :|..::..:           .||..:|.:::....::|.....|.: |.|:.|.|
  Rat   676 ---------LQLFVENPS-----------EEDAAIVDKILACRTVKKEVSPGVML-DIEEFFVK- 718

  Fly   317 AHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQ------------SNVPAVRVVKPTLNPPR 369
                       .|....|..|.|.::|.:...|:||            ::..|....:| .||
  Rat   719 -----------YKNYSYLHCEWATEQQLLKDKRIQQKIKRFKLRQAQRAHFLADMEEEP-FNP-- 769

  Fly   370 APSIDTLDWDELSEAVNEIKPVYTGAQGM-------------ATFNNQKALTLESLKDLHVSLED 421
                |.::.|.:.| |:..:...||...:             :|:..::.:.|..:::.......
  Rat   770 ----DYVEVDRILE-VSFCEDKDTGESVVYYLVKWCSLPYEDSTWELKEDVDLAKIEEFEQLQAS 829

  Fly   422 LPGPEVLAEDPVGL--KV----------SLMNHQKHALAWM--SWRERKLPRGGILADDMGLGKT 472
            .|....|...|..:  |:          .|..:|...|.|:  :|..|   |..||||:||||||
  Rat   830 RPDTRQLDRPPSNIWKKIDQSREYKNGNQLREYQLEGLNWLLFNWYNR---RNCILADEMGLGKT 891

  Fly   473 ---LTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPAS 534
               :|.:..||                              :||         .||..|::.|.|
  Rat   892 IQSITFLYEVL------------------------------LTG---------IRGPFLIIAPLS 917

  Fly   535 LLRQWESEVESKVSRQKLTVCVHHGN-------------NRETKGKYLRD---YDIVVTTYQIVA 583
            .:..||.|..:...   :.|.|:||:             .|:::|:.:|.   :..::||::::.
  Rat   918 TIANWEREFRTWTD---INVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYRFQAIITTFEMIL 979

  Fly   584 REHKSLSAVFGVKWRRIILDEAHVVRNH--KSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALL 646
            .....|:|   ::||.:|:||||.::|.  |....|.:.:|  :::..|||||:||...::::||
  Rat   980 GGCGELNA---IEWRCVIIDEAHRLKNKNCKLLEGLKLMNL--EHKVLLTGTPLQNTVEELFSLL 1039

  Fly   647 KFLRCSPFDDLHTW-KKWIDNKSAGGQNRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEI 710
            .||....|....|: :::.|.|:.....:|..::|.:||||.|..::     ..|..||..:||:
  Rat  1040 HFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVE-----KRLAPKEETIIEV 1099

  Fly   711 SLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFAR 775
            .|...:...|:.::                 |.:|::.|..    ..|...||
  Rat  1100 ELTNIQKKYYRAIL-----------------EKNFSFLSKG----AGQTNVPN------------ 1131

  Fly   776 MAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGD-----HSSDSDTPEIDLLAQL 835
                        ::..::.||:.|.||.||    .|.|.:.:|:     :.|.||.....::...
  Rat  1132 ------------LVNTMMELRKCCNHPYLI----KGAEEKIIGEFRDTYNPSASDFHLQAMIQSA 1180

  Fly   836 NKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILK 900
            .||.:.|                 .|||.
  Rat  1181 GKLVLID-----------------KLLPK------------------------------------ 1192

  Fly   901 TSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLL 965
               :|:...|.::.||....||||.|:|.........::|.:....||..::.|:..::.:.|.|
  Rat  1193 ---MKAGGHKVLIFSQMVRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFL 1254

  Fly   966 LSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQ 1030
            |...|||:|:||..|:..::.|..||||.:.|||.|.:|:||.|.|.:|:.:..::.|:.:....
  Rat  1255 LCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRA 1319

  Fly  1031 DKKLDLADGVL----------TGAKVSSKLTIDDL--KGLFG 1060
            ..||.|...||          :|.:..||..|:||  :|.:|
  Rat  1320 SLKLGLDKAVLQSMSGRDSNVSGIQQLSKKEIEDLLRRGAYG 1361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	180/819 (22%)
		DEXHc_TTF2	439..686	CDD:350830	71/270 (26%)
Chd9	XP_038953982.1	KLF3_N	217..375	CDD:410554
		PTZ00121	<510..>765	CDD:173412	61/345 (18%)
		CD1_tandem_CHD5-9_like	685..749	CDD:349315	17/76 (22%)
		CD2_tandem_CHD5-9_like	769..827	CDD:349310	9/64 (14%)
		PLN03142	858..>1479	CDD:215601	159/664 (24%)
		BRK	2475..2515	CDD:462196
		BRK	2549..2593	CDD:197800