Protein Alignment lds and smarca5

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001075098.2
• Gene: smarca5 / 282615
• ZFINID: ZDB-GENE-021125-1
• Length: 1035
• Species: Danio rerio
• Alignment Length: 894
• Identity: 209/894 - (23%)
• Similarity: 331/894 - (37%)
• Gaps: 317/894 - (35%)

  Fly   206 KETPIEI--LSSTDDDATTN-KENMSGPPFERPSKSLSPRSSAGASV-------VKTSK------ 254
            :|.|.::  ....:||.:.| .:..|....:..::|.||.|:.|..:       |:|.:
Zfish    13 EEEPSQLDPAGPAEDDTSENGHDEASDTAMDSEAQSSSPPSAKGKDLLGGYEEKVQTDRTNRFEY 77

  Fly   255 ---------NLSQPTIQAVLKQKTSP--AAPRRSRI-KSEDQKVVSQVVYDEEMRKLAEKRVQVS 307
                     :..||..|   |..|||  ..|.|.|| |.|.|.::|  ..|...|:..    |..
Zfish    78 LLKQTEVFAHFIQPAAQ---KTPTSPLKMKPGRPRIKKDEKQNLLS--AGDNRHRRTE----QEE 133

  Fly   308 DAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVPAVRVVKPTLNPPRAPS 372
            |.|.|.|.      .|.:.:..|.|.                                    :||
Zfish   134 DEELLSEN------SKATSVCTRFDD------------------------------------SPS 156

  Fly   373 IDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLKV 437
            .                 |.||
Zfish   157 Y-----------------VKTG------------------------------------------- 161

  Fly   438 SLMNHQKHALAWM-SWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSE 501
            .|.::|...|.|: |..|..:  .|||||:|||||||..||.:...|:.:.:.
Zfish   162 KLRDYQVRGLNWLISLYENGI--NGILADEMGLGKTLQTISLLGYMKHYRNIP------------ 212

  Fly   502 DDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKG 566
                                   |..:|:.|.|.|..|.:|.:..|...| .||:.  .:||.:.
Zfish   213 -----------------------GPHMVLVPKSTLYNWMNEFKRWVPSLK-AVCLI--GDREERT 251

  Fly   567 KYLRD------YDIVVTTYQIVAREHKSLSAVF-GVKWRRIILDEAHVVRNHKSQSSLAVCDLRG 624
            .::||      :|:.||:|:::..|.    ||| ...||.:::||||.::|.||:.|..|.:.:.
Zfish   252 AFIRDTLLPGEWDVCVTSYEMLIIER----AVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKT 312

  Fly   625 KYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ----NRLNLLMKSLMLR 685
            ..|..|||||:||...:::|||.||....|:....:..|.|..:..|.    .||:.:::..:||
Zfish   313 TNRLLLTGTPLQNNLHELWALLNFLLPDVFNSSEDFDAWFDTNNCLGDTKLVERLHTVLRPFLLR 377

  Fly   686 RTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSD 750
            |.||.::.    :.||.||:: |.:.|.|.:...|..::
Zfish   378 RIKADVEK----SLLPKKEIK-IYVGLSKMQREWYTKIL-------------------------- 411

  Fly   751 ANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQ 815
                    :||.:         ....||...:::   :|.:|::||:.|.||.|.|
Zfish   412 --------MKDID---------ILNSAGKMDKMR---LLNVLMQLRKCCNHPYLFD--------- 447

  Fly   816 TMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSN 880
              |.......|.::.|:....|:.:.|                 .|||.
Zfish   448 --GAEPGPPYTTDLHLVVNSGKMVVLD-----------------KLLPK---------------- 477

  Fly   881 PVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVK 945
                                   ||....:.::.||.|.|||||.|:..........|:|..|.:
Zfish   478 -----------------------LKEQGSRVLIFSQMTRVLDILEDYCMWRNYGYCRLDGQTPHE 519

  Fly   946 NRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKN 1010
            .||..:|.||:.|:.|.:.:||..|||:|:||..|:.:::.|..||||::.||.||.:|:||||.
Zfish   520 ERQISINAFNEPNSSKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQVDLQAMDRAHRIGQKKQ 584

  Fly  1011 VIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKV----SSKLTIDDL 1055
            |.:::|:..:|||:||....:.||.|...|:...::    .:||..|::
Zfish   585 VRVFRFITDNTVEERIVERAEMKLRLDSIVIQQGRLVDPSMNKLGKDEM 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	178/765 (23%)
		DEXHc_TTF2	439..686	CDD:350830	75/258 (29%)
smarca5	NP_001075098.2	PLN03142	4..1030	CDD:215601	209/894 (23%)