Protein Alignment lds and RAD54B

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_036547.1
• Gene: RAD54B / 25788
• HGNCID: 17228
• Length: 910
• Species: Homo sapiens
• Alignment Length: 661
• Identity: 173/661 - (26%)
• Similarity: 274/661 - (41%)
• Gaps: 168/661 - (25%)

  Fly   431 DPVGLKVSLMNHQKHALAW---------MSWRERKLPRGGILADDMGLGKTLTMISSV--LACKN 484
            ||. |...|..|||..:.:         |:.|     .|.||||:|||||||..||.:  |.|:.
Human   289 DPY-LVYHLRPHQKEGIIFLYECVMGMRMNGR-----CGAILADEMGLGKTLQCISLIWTLQCQG 347

  Fly   485 GQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSR 549
            ..                          |.|...:|      ||:|.|.||:..|:.|.:..:..
Human   348 PY--------------------------GGKPVIKK------TLIVTPGSLVNNWKKEFQKWLGS 380

  Fly   550 QKL---TVCVHHGNNRETKGKYLRDYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNH 611
            :::   ||...|......|..:   |.:::.:|:::.|   ||..:..:|:..:|.||.|.::|.
Human   381 ERIKIFTVDQDHKVEEFIKSIF---YSVLIISYEMLLR---SLDQIKNIKFDLLICDEGHRLKNS 439

  Fly   612 KSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWID-------NKSA 669
            ..:::.|:..|..:.|..||||||||...:.:||:.|:.......|.:::|..:       ..||
Human   440 AIKTTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSA 504

  Fly   670 G------GQNR---LNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMT 725
            .      |:.|   |..|....:||||:..:.     ..||.|...::.......::.:|:.::.
Human   505 SEEEKELGERRAAELTCLTGLFILRRTQEIIN-----KYLPPKIENVVFCRPGALQIELYRKLLN 564

  Fly   726 YSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILV 790
            .....|.  |....|           |.|                               |  |:
Human   565 SQVVRFC--LQGLLE-----------NSP-------------------------------H--LI 583

  Fly   791 LLLRLRQICCHPGLIDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAG 855
            .:..|:::|.||.|:...:..:|..:..|.:.:.         .|.|         |..||..|
Human   584 CIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEK---------SLYK---------GLLSVFPA- 629

  Fly   856 DDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSV 920
             |..|||..|....|.               :..||:..||..|:.:      :|.::||.:|..
Human   630 -DYNPLLFTEKESGKL---------------QVLSKLLAVIHELRPT------EKVVLVSNYTQT 672

  Fly   921 LDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLL 985
            |:||::...:.|.|...|:|..|:..||.||:.||.:::...:.|||..||||||||||.:||:|
Human   673 LNILQEVCKRHGYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLIL 737

  Fly   986 LDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSS-- 1048
            .|:.|||..:.||..|::|.|||..|.||:.:...|:|::|...|..|..|...|:...|.|.
Human   738 YDIDWNPATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHI 802

  Fly  1049 KLTIDDLKGLF 1059
            :.::::||.||
Human   803 QFSVEELKNLF 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	166/639 (26%)
		DEXHc_TTF2	439..686	CDD:350830	71/276 (26%)
RAD54B	NP_036547.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		HepA	<296..794	CDD:440319	164/632 (26%)
		DEXHc_RAD54B	296..530	CDD:350824	71/276 (26%)
		DEGH box	431..434		2/2 (100%)