Protein Alignment lds and C25F9.5

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_507777.2
• Gene: C25F9.5 / 180272
• WormBaseID: WBGene00007725
• Length: 713
• Species: Caenorhabditis elegans
• Alignment Length: 669
• Identity: 138/669 - (20%)
• Similarity: 222/669 - (33%)
• Gaps: 234/669 - (34%)

  Fly   495 SSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVE----SKVSRQK---- 551
            |||||.::.....:      |.:.|||:   |.::..|.|     :||::    |.:..||
 Worm     2 SSDSDMKNVMQDLK------KLENRKDS---GGIITVPTS-----DSEIDQVIISYILEQKEQGT 52

  Fly   552 -----------------------------------LTVCVHHGNNRETKGKYLRDYDIVVTTYQI 581
                                               |.:...:...:......|...|||:|||..
 Worm    53 SENNINLIVGTPKWIKSWNLKFNGFIRAGILKDDDLLISYFYNRTKSRSSNELAKNDIVITTYDT 117

  Fly   582 VAREHKSLSAVF-GVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYAL 645
            :  :.||...:| .|.|.||||.||:.:.:..:....|:|:|:.||||.||      :....::|
 Worm   118 L--KTKSNLPIFKAVDWERIILYEANKISDINTLRFGAICELKSKYRWCLT------ENFKQHSL 174

  Fly   646 LKFLRCSPFDDLHTWKKWIDNKSAGGQNRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEI 710
            ..||:....|.                           .:.||          ||...:|.:.:|
 Worm   175 AFFLKMYDVDS---------------------------FKNTK----------SLEEHKLLVKDI 202

  Fly   711 SLDKEEMNVY--QTVMTYSRTLFA------QFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYY 767
            ..|.|::|:|  .|.:...|..|.      :|.:..|:.|.:..||:.|               |
 Worm   203 EKDLEQVNLYWSSTELKMKRINFVLKPRQKEFTNSLAQCEAESTYRTTA---------------Y 252

  Fly   768 KMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEE-----SQTMGD----HSSD 823
            .|:|...|.:                          :|..:||.:|     |:.||.    .|.|
 Worm   253 GMNEDEIRKS--------------------------IIAFLLDQDEKSERSSRAMGKTLLVMSPD 291

  Fly   824 SDTPEIDLLAQLNK---LAI------TDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRS 879
            ...|..:||..|.|   |||      |..|.:....|....|          |..|:.|..::..
 Worm   292 VIKPWKELLESLLKEDYLAINYYGNETKKSNNSHVVVITTYD----------RFEKSYKKYIQWE 346

  Fly   880 NPVF-NLHRPSSKINMVIQ-ILKTSI------------------LKSSDDKA---IVVSQWTSVL 921
            ..:| .....::|.|...| :|:.|:                  ||.::||.   :||:.....|
 Worm   347 RIIFYGFSLANAKCNQHYQKLLQLSVMHRWCLTEENTHRFSAHFLKGNNDKIGEDVVVNNIEQKL 411

  Fly   922 DILRD-----HLSKDGVATLSLNGTIPVKNR--QDIVN---EF----------NDRNNQKRVLLL 966
            .:|..     .|....:.....|......|.  :.||:   ||          .|.:.::...::
 Worm   412 HLLSTTKYYFTLMTSAIKASKANDCCQFSNDMWESIVSYTKEFFYKNFEIWLKEDESLEEMYEMM 476

  Fly   967 SLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQD 1031
            .|...|....||   ..|.:|::||.  .|...|..:....:.:.|      ||..::.|...::
 Worm   477 CLGLDGSAAALI---IRLWVDVNWNH--TACKHDSFFITRDEMDDI------VDRWKKSIDLTEN 530

  Fly  1032 KKLDLADGVLTGAKVSSKL 1050
            ..:||...||...|:...|
 Worm   531 AHIDLIRNVLIEKKLLQDL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	134/658 (20%)
		DEXHc_TTF2	439..686	CDD:350830	49/234 (21%)
C25F9.5	NP_507777.2	DEAD-like_helicase_N	<41..>166	CDD:475120	29/126 (23%)
		DEAD-like_helicase_N	<271..>379	CDD:475120	27/117 (23%)