Protein Alignment lds and rad-54.L2

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_501545.1
• Gene: rad-54.L2 / 177706
• WormBaseID: WBGene00007761
• Length: 1274
• Species: Caenorhabditis elegans
• Alignment Length: 1159
• Identity: 237/1159 - (20%)
• Similarity: 415/1159 - (35%)
• Gaps: 360/1159 - (31%)

  Fly    56 SEE-EESQSSETAESEKSDESDNSQNSQESEDSEDDSVR---PSARNTKRKPLGIPSDSED-EED 115
            ||| :|:...|..|.|:.||.:..:...:::..|..::|   .:.::.|||.:.....:|| :|:
 Worm     2 SEEIDENTMKEEQEEEERDEIEEKEEKPDAQQQELLNIRIPTQTKKSLKRKHIKTDFGAEDLDEN 66

  Fly   116 ELEQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQ--EGPTEAPTAEAVVPRYTTQ------- 171
            .||.:.|.......:..::|:           :|.:|  |....|..:|..:|:...|
 Worm    67 VLEAQRLEKQRLERLEKIKPE-----------NDHIQQMESLFLAGASEGQLPQLDLQDDDFEEM 120

  Fly   172 FAGNIQNDLHSTIGAADSEV------LDDSSGS----DVLILSNKETPIEILSSTDDDATTNKEN 226
            |..:::|| :......|.|.      |.:.|.|    ||:.|:        |..:|||.
 Worm   121 FGFSVEND-NKKYRYGDEEKPEPMFHLQEPSTSRGHVDVVDLT--------LDDSDDDC------ 170

  Fly   227 MSGPPFERPSKSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVV 291
                                                                :.::.:.|:.|||
 Worm   171 ----------------------------------------------------LITDVKSVMPQVV 183

  Fly   292 YDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQSNVP 356
                    ..:|::.:.|||                 .|||..:.::             |.|:.
 Worm   184 --------PGRRMRWAQAEK-----------------DRIDADQMDI-------------QHNIE 210

  Fly   357 AVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLKDLHVSLED 421
            |.|:.|                                              :.|.|||. |.|.
 Worm   211 ARRLKK----------------------------------------------MRSAKDLE-STEK 228

  Fly   422 LPG--------PEVLAEDPVGLKVSLMNH--QKHALAWM---------SWRERKLPR--GGILAD 465
            ..|        ||   |||....:|.:.|  |.|.|..:         |..|.|...  |.|||.
 Worm   229 KEGRLLVNAGHPE---EDPDIFVISHLTHVLQPHQLGGIRFMYDNTIESLGEYKKSDGFGCILAH 290

  Fly   466 DMGLGKTLTMI--SSVLACKNGQEMSEGK--------DESSDSDSEDDKNKKRKSVTGWKSK--- 517
            .||||||:.:|  |.:..     ..::.|        :...:..||.||...:.|.||.:.:
 Worm   291 SMGLGKTIQVITFSEIFL-----RATKAKKVLVIVPINTIQNWYSEYDKWIPKFSDTGDRIRSFE 350

  Fly   518 ------GRK--DTRRGGTLVVCPASLLRQWES--------------------EVESKVSRQKLTV 554
                  |.|  |.|         .:|:.||:.                    ..:.|..|.||.:
 Worm   351 VFLLGDGVKTFDQR---------VNLIEQWDQTGGVMLVGYDMFRLLIKMTLPKKQKKGRPKLNL 406

  Fly   555 C-VHHGNNRE-TKGKYLRD----YDIVVTTYQIVAREHKSL--SAVFGVKWRRIILDEAHVVRNH 611
            . :..|.::: ::.:.|||    ::...|:...|.:|..||  ||:.......::.||.|.::|.
 Worm   407 SGISSGFSKDSSEDQKLRDEELEFETGFTSGGRVRQEAYSLIRSALLEPGPDLVVCDEGHKIKNI 471

  Fly   612 KSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDN---------- 666
            .::.|:.:..:..|.|..|||.|:||..|:.:.::.|:|..   .|.|.|.:||.
 Worm   472 TAEISMTLGAINTKRRIVLTGYPLQNNLLEYFCMIDFVRPK---YLGTRKSFIDRFEKPIKNGQC 533

  Fly   667 -KSAGGQNRLNL--------LMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQT 722
             .|:....::.|        |:|..:.|||...|:     ..||..:..::.:...:.:..:|:.
 Worm   534 VDSSPDDVKIALQRTHVLVELVKGFVQRRTHHLLK-----KILPESKEYVLLLRKSQIQRQLYRN 593

  Fly   723 VMTYSRTLFAQFLHQRAERETDFN--YRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKS 785
            .:.:::...|      |..:..||  ....|....:|.   |: ..|::.|:..|....||.|:.
 Worm   594 FVLWAKNEIA------ANNDAVFNPLMAFSACSKIWNH---PD-ILYRLVEQKKRAEEDKKRVEQ 648

  Fly   786 HDILVL-------------LLRLRQICCHPGL---IDAMLDGEESQTMGDHSSDSDTPEIDLLAQ 834
            .....|             ::.:......||.   .....:|...|....|.::...|     :.
 Worm   649 MKFAQLQQQQQQQQQQLQGMMMMGNNGMMPGFGAQFHPQQNGMMMQNGSWHPNNYQMP-----SP 708

  Fly   835 LNKL-------AITDTSTDGQQSVANAGDDGPPLLPDE-ARIAKASKNLLKRSNPVFNLHRPSSK 891
            .|.:       ..:.||...:::....|....|...:| ..:.|.|:.....:..:|..::....
 Worm   709 FNSIPSNPSTPTSSSTSKSAKKTKKPRGSKKAPKSDEEDEEVEKESRMKYDWTFELFEKYQEGVL 773

  Fly   892 INMVIQILKTSILKSS---DDKAIVVSQWTSVLDILRDHL------SKDGVAT--------LSLN 939
            .|....::...||..|   .:|.::.||..:.||:|.:.|      .|||...        |.|:
 Worm   774 ENGYKIVISLEILDESTQIGEKILIFSQNLTALDMLEEILKKRQIRGKDGPGQRWEKNRNYLRLD 838

  Fly   940 GTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYR 1004
            ||....:|:.::|.||...... :.|:|..||.:|:||:.||..:::|..|||..:|||..|:||
 Worm   839 GTTSGADREKLINRFNSEPGLS-LFLISTRAGSLGINLVSANRCIIIDACWNPCHDAQAVCRVYR 902

  Fly  1005 VGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKGL 1058
            .||:|...:|:.:..:::|:.|...|..|..|...|:..|:|.:.::..:|:.|
 Worm   903 YGQQKKTFVYRLIMDNSMERSIFNRQISKHGLQQRVVDDAQVDANISQKELETL 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	188/885 (21%)
		DEXHc_TTF2	439..686	CDD:350830	74/327 (23%)
rad-54.L2	NP_501545.1	HepA	60..940	CDD:440319	219/1083 (20%)
		DEXHc_ARIP4	256..547	CDD:350827	71/307 (23%)