Protein Alignment lds and isw-1

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_001379931.1
• Gene: isw-1 / 175944
• WormBaseID: WBGene00002169
• Length: 1009
• Species: Caenorhabditis elegans
• Alignment Length: 749
• Identity: 170/749 - (22%)
• Similarity: 291/749 - (38%)
• Gaps: 231/749 - (30%)

  Fly   353 SNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIK---------------------------P 390
            ||:|.        :....||::..|..|.|:|.:..|                           |
 Worm    19 SNIPE--------SSGNDPSMEVDDEPESSDAADSFKRFERLLQKTENFSHCLSSGDAKLATGAP 75

  Fly   391 VYTGAQGMATFNN-----QKALTLESLKDLHVSLEDLPGPEVLAEDPVGLKVS--------LMNH 442
            |.|..:|..:..|     .:....|..:|     |::....:.::|.|....|        :.::
 Worm    76 VDTKKRGRPSKKNGIDGDHRHRKTEQEED-----EEMVADAIKSDDLVIFDKSPFYIENGEMRDY 135

  Fly   443 QKHALAWM-SWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNK 506
            |...|.|: |.:..|:  .|||||:|||||||..||.:...|:
 Worm   136 QVRGLNWLASLQHNKI--NGILADEMGLGKTLQTISMIGYMKH---------------------- 176

  Fly   507 KRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETKGKYLRD 571
                   :|:|....      ||:.|.|.|:.|.:|.:.........|.:   .:...:.:.|||
 Worm   177 -------YKNKASPH------LVIVPKSTLQNWANEFKKWCPSINAVVLI---GDEAARNQVLRD 225

  Fly   572 ------YDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWAL 630
                  :|:..|||:::.:....|..   :.||.||:||||.::|.||:.|..|.:|..:.|..:
 Worm   226 VILPQKFDVCCTTYEMMLKVKTQLKK---LNWRYIIIDEAHRIKNEKSKLSETVRELNSENRLLI 287

  Fly   631 TGTPIQNKELDVYALLKFLRCSPFDDLHTWKKWIDNKSAGGQ----NRLNLLMKSLMLRRTKAQL 691
            ||||:||...:::|||.||....|.....:..|..|.:..|.    .||:.:::..:|||.|
 Worm   288 TGTPLQNNLHELWALLNFLLPDIFTSSDDFDSWFSNDAMSGNTDLVQRLHKVLQPFLLRRIK--- 349

  Fly   692 QSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTY 756
             ||.:.:.||.||:: :.:.|.|.:...|..|:
 Worm   350 -SDVEKSLLPKKEVK-VYVGLSKMQREWYTKVL-------------------------------- 380

  Fly   757 NQIKD---PNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMG 818
              :||   .|||               .:|:...::.:|:.||:...||.|.|
 Worm   381 --MKDIDIINGA---------------GKVEKARLMNILMHLRKCVNHPYLFD------------ 416

  Fly   819 DHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVF 883
                                               ..:.|||...|:..:..:.|
 Worm   417 -----------------------------------GAEPGPPFTTDQHLVDNSGK---------- 436

  Fly   884 NLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQ 948
                      ||:........|....:.::.||::.:||:|.|...........|:|:.|.::|.
 Worm   437 ----------MVVLDKLLMKFKEQGSRVLIFSQFSRMLDLLEDFCWWRHYEYCRLDGSTPHEDRS 491

  Fly   949 DIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVII 1013
            :.:..:|..:::|.:.:|:..|||:|:||..|:.:::.|..||||.:.||.||.:|:||||.|.:
 Worm   492 NAIEAYNAPDSKKFIFMLTTRAGGLGINLATADVVIIYDSDWNPQSDLQAMDRAHRIGQKKQVRV 556

  Fly  1014 YKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVS 1047
            ::.:..:||::||....:.||.|.:.|:...::|
 Worm   557 FRLITENTVDERIIEKAEAKLRLDNIVIQQGRMS 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	168/741 (23%)
		DEXHc_TTF2	439..686	CDD:350830	71/257 (28%)
isw-1	NP_001379931.1	PLN03142	48..1008	CDD:215601	160/712 (22%)