Protein Alignment lds and btf-1

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: NP_496802.2
• Gene: btf-1 / 174965
• WormBaseID: WBGene00000274
• Length: 1649
• Species: Caenorhabditis elegans
• Alignment Length: 1116
• Identity: 253/1116 - (22%)
• Similarity: 414/1116 - (37%)
• Gaps: 350/1116 - (31%)

  Fly    76 DNSQNSQESEDSEDDS------VRPSARNTKRKPLGIPSDSEDEEDELEQRALSPSTRMSI--TG 132
            |.:......|..||.|      |||:.:..|::      :|.|.......|::. :.:|:|  .|
 Worm   698 DRTSAEARGESPEDVSKAAYSIVRPNLKTEKQR------ESIDSRYNTLCRSIE-NAKMNIKSNG 755

  Fly   133 VRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSG 197
            :|...|.  .|.:.|.....|..|  |....:|....|:     :||      |..|||.   .|
 Worm   756 IRINALL--SSTLFYFGNAPEKLT--PQIRPIVETMQTE-----END------AMASEVF---RG 802

  Fly   198 SDVLIL-----SNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKTSKNLS 257
            :..|::     .|....:::.:..       .|:.||.|...|...   .||.||....|:..:|
 Worm   803 AVPLLVMFSWSRNPRPYVKVFAKA-------FESFSGCPIRMPKLG---ASSPGALEPWTTTIIS 857

  Fly   258 QPTIQAVLKQKTSPAAPRRSRI---KSEDQKVVSQVVYDEEMRKLAE------------------ 301
               ::.:..::|.......|.:   :|.:.::...::......:|||
 Worm   858 ---MRRIWGKETDDGFEESSGMISAESRNAELFLNILCQFNASQLAEFYCHFDLSEDVDLNTFLT 919

  Fly   302 -------------KRVQVSDAEKLFEKVAHKLP-------------------DKGSQIMKRIDTL 334
                         .|:....|:|:|..|..:.|                   |..|:...|:..|
 Worm   920 RLELHNSLWNRVGSRLSDQSADKIFSLVPSEDPAIRYAFAKAIETFFKSSCGDTLSKCYNRLVVL 984

  Fly   335 RRELAMDEQWISALRV---------QQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKP 390
            .::|......:||:.|         :..|..|. ::.|.:.|..|...:|:. |...||...:.|
 Worm   985 SKDLDNVNSRLSAVEVFLRLCMMDTRYLNGWAT-LLAPVIFPLLADQCETVR-DAAGEAFRRLIP 1047

  Fly   391 VYT------GAQGMATFNNQKALTLESLKDLHVSLEDLPG--PEVLAED-PVGLKVSLM-NHQKH 445
            |.|      ..:||    :|:.|..:|.....:::...|.  |.|:..| ..|...|:: .:|..
 Worm  1048 VITLENPDFSIEGM----SQELLAKKSEYSNFINVLGSPSSLPRVIRADIRGGFDTSMLREYQLE 1108

  Fly   446 ALAWMSWRERKLPRGGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKS 510
            .:.|:.:. |.....|||||||||||||..:.|:....:..||||....|
 Worm  1109 GITWIRFL-RTYGLHGILADDMGLGKTLQTMCSIALSVDRDEMSEFHRCS--------------- 1157

  Fly   511 VTGWKSKGRKDTRRGGTLVVCPASLLRQWESE----VESKVSRQK-LTVCVHHGNNRETKGKYLR 570
                             |:|||.:|:..|..|    ...:|...| ||.|  ||
 Worm  1158 -----------------LIVCPRTLVDHWCLEWNRFFPQRVPASKNLTRC--HG----------- 1192

  Fly   571 DYDIVVTTYQIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPI 635
             .:|.|..|.    |.|:...:..| |..|:|||.||:||.|.::......|.||.|..|:|||:
 Worm  1193 -AEICVIAYD----ELKTAYMMDRV-WNYIVLDEGHVMRNSKLRAWKFASQLVGKSRLILSGTPV 1251

  Fly   636 QNKELDVYALL--------------------KFLRC----SPFDDLHTWKKWIDNKSAGGQ--NR 674
            ||...|:::|.                    |.::|    :...||          .||..  ::
 Worm  1252 QNSPADLWSLFAWLMPGYLGSEKQFRSQFLKKIMKCRLPKANEADL----------KAGSAAISQ 1306

  Fly   675 LNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRA 739
            |:.|:...::||.|.::     |..||.|.::..|..|.:::..:|:.|:.
 Worm  1307 LHKLVLPFVMRRLKTEV-----LKELPEKNVQDYECELTEDQKEIYRFVVD-------------- 1352

  Fly   740 ERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGSKKEVKSHDILVLLLRLRQICCHPGL 804
                                               |...|:::| ....||.|:.||::..|..|
 Worm  1353 -----------------------------------RCTSSQEDV-GLSSLVTLITLRKLTDHTKL 1381

  Fly   805 IDAMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTDGQQSVANAGDDGPPLLPDEARIA 869
            :.                       |.||::.                     .|..:..:|..|
 Worm  1382 VH-----------------------DTLAKIG---------------------APQYILSKALAA 1402

  Fly   870 KASK-NLLKR--------SNPVFNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLDILR 925
            |:.| ..||:        .||...:.:|.....:|          :|..:|::..||.:...::.
 Worm  1403 KSGKMEALKQLLIECEICKNPDEEVEQPEDLGGLV----------ASGHRALIFCQWKTSAKLVS 1457

  Fly   926 DHLSKDG-----VATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLL 985
            |.| |.|     |:.|.|:|::|..:|..:||.||: :....||:|:...|||||||.||:.::.
 Worm  1458 DAL-KSGEFGSVVSHLVLDGSVPAGDRMKMVNRFNE-DKTIDVLILTTHVGGVGLNLTGADTVIF 1520

  Fly   986 LDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGAKVSSKL 1050
            ||..|||..:.||.||.:|:||.:||.:|:.:...|||:::..|...||:.|. .|.||..:|.:
 Worm  1521 LDHDWNPMKDLQAIDRAHRLGQTRNVNVYRLITQGTVEEKVMSLAKFKLNTAQ-ALIGADNTSMM 1584

  Fly  1051 TID--DLKGLF 1059
            |::  :|..:|
 Worm  1585 TMETGELMNMF 1595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	199/867 (23%)
		DEXHc_TTF2	439..686	CDD:350830	72/278 (26%)
btf-1	NP_496802.2	DUF3535	<572..>792	CDD:463447	24/109 (22%)
		HepA	<1102..1577	CDD:440319	160/648 (25%)