Protein Alignment lds and LOC1271255

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_061510596.1
• Gene: LOC1271255 / 1271255
• VectorBaseID: AGAMI1_006303
• Length: 3078
• Species: Anopheles gambiae
• Alignment Length: 1272
• Identity: 261/1272 - (20%)
• Similarity: 449/1272 - (35%)
• Gaps: 382/1272 - (30%)

  Fly     1 MSSENSEYYSDKEEDSVVNNSSL--------GRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSE 57
            |:....|.|.|.:.:.:.|.|:|        |.:......|.:|:..:||..::|....||...|
Mosquito   652 MTEAEREEYEDMQIERLCNISTLIGCRNAAGGAAGSGGPTSAASKSKESSSSAAAKKKKDENNME 716

  Fly    58 E---------------EESQSSETAESEK------------------------------------ 71
            .               .|.||.|::||||
Mosquito   717 HFLNHENGSDDTATAPLEPQSDESSESEKDVVETEEQFLQKCNETMKQQLLNQLSSSEETSEEED 781

  Fly    72 --------SDESDNS----QNSQESEDSEDDSV-------------RPSARNTKRKPL------- 104
                    .:|.|||    .|....|||:|.|.             :.:.|..::|.|
Mosquito   782 NLDGLLSGEEEDDNSADGRPNGTGKEDSDDSSAGSLVESFLKRHDSKLAERKERKKQLNERENGN 846

  Fly   105 ----GIPSDSEDE---EDELEQRALSPS---------TRMSITGVRPQDL-SDDDSEIEYSDEVQ 152
                |...||.|.   |...||:|...|         ||..:...:.::| |:|..:.|.||:.:
Mosquito   847 LLTNGQADDSGDNIGGESSAEQQATKDSERAETPKKQTRTELANPKDKELFSNDLFDGEKSDKSE 911

  Fly   153 EGPTEAPTAEAVVPRYTTQFAGNIQNDLHSTIGAADSEVLDDSSGSDVLILSNKETPIEILSSTD 217
            :.|.:..      .|...:.|...:::..|:...:|.|:||   |:.......:..|:. |.:.|
Mosquito   912 KTPRKRR------KRINARKARGSESERESSSADSDLEMLD---GTPKKRQRKRAAPVS-LETFD 966

  Fly   218 DDATTNKENMSGPPFERPSKSLSPRSSA--GASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIK 280
            ..|:.|..       ..|.||.:|.|:|  |:::.|.|.:             |:|:.   ..||
Mosquito   967 FSASLNAS-------AAPRKSKTPASTACEGSTIAKPSPS-------------TTPSG---DGIK 1008

  Fly   281 SEDQKVVSQVVYDEEMRKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWI 345
            .:..|..|....|.:...........:.:.   ...|.|  .|||:..:...:|..:.:.|.:.|
Mosquito  1009 GKQAKTSSPAPSDPDATTTGSGAAATAASG---SSTAGK--QKGSKDGQDCISLSSDSSDDAELI 1068

  Fly   346 SALRVQQSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLE 410
            :....:...||.        ..|:......|..|||:|   |.|......:|......:|.   |
Mosquito  1069 TGDLEENKTVPD--------KEPKRRIRAMLTNDELAE---ETKKAQKEEEGRTARLKKKH---E 1119

  Fly   411 SLKDLHVSLEDLPGP--------------EVLAEDPVGLKVSLMNHQKHALAWM----SWRERKL 457
            .||....|.  ||||              :.:...|..:|: |..||...:.:|    ......|
Mosquito  1120 QLKKFLASY--LPGPGESELVLDYDSVRKQAICVHPEIVKL-LKPHQIEGIKFMYDNTYGSVDAL 1181

  Fly   458 PR----GGILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKG 518
            |:    |.|||..|||||||.|||.:.......::...:
Mosquito  1182 PKHSGSGCILAHCMGLGKTLQMISLLHTVMRYPQLMTNR-------------------------- 1220

  Fly   519 RKDTRRGGTLVVCPASLLRQWESEVES-----KVSRQKLTVCVHHGNNRETKGKYLRDY------ 572
                    .||:||.|.:..|:.|:..     :...|....|......:..|...|:.:
Mosquito  1221 --------VLVICPKSTVMNWKEEIARWQGTIRTGYQMKVYCFPDVCTQNDKIAVLKRWYYCKSP 1277

  Fly   573 --DIVVTTYQ----IVAREHKSLSAVFGVKWRR---------------IILDEAHVVRNHKSQSS 616
              .:::..|:    ::..|.:..|.  |::..:               :|.||.|.::|.:|..|
Mosquito  1278 NCGVMLIGYEAFRALINYERRKGSV--GLRSAKLGLIKEYLLNPGADLVICDEGHQIKNKRSAIS 1340

  Fly   617 LAVCDLRGKYRWALTGTPIQNKELDVYALLKFLRCS------PFDDLHTWKKWIDNKSAGGQNRL 675
            .||..::.:.|..||||||||...:.|.::.|::.|      .|.:|:.      |....||.:
Mosquito  1341 EAVSKIKTRRRIMLTGTPIQNNLKEYYCMVNFIKPSFLGSDKEFSNLYA------NPIKNGQCK- 1398

  Fly   676 NLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDKEEMNVYQTVMTYSRTLFAQFLHQRAE 740
            :...:|:.:.:.::.:        |.||..:.::    ::|..|.:           :||.::.|
Mosquito  1399 DSDHQSIKIMKQRSYV--------LHNKLSKFVQ----RKEAAVLK-----------EFLPEKFE 1440

  Fly   741 RETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARM--------AGSKKEVKSHDILVLLLRLRQ 797
                           |...........||:|.|.:|        .|.....|...::.....||:
Mosquito  1441 ---------------YVLFVPLTPVQEKMYEVFLQMNDYTNNDVTGEPGRTKKFKLIADYTSLRK 1490

  Fly   798 ICCHPGLID-AMLDGEESQTMGDHSSDSDTPEIDLLAQLNKLAITDTSTD-------GQQSVANA 854
            |..||.::: |.......:...|.:..:.||:.|           |.|.|       ||.||.|
Mosquito  1491 IWTHPKVLEKAWESANLEKNRRDAARKTATPDSD-----------DESPDDHNDIKSGQLSVTN- 1543

  Fly   855 GDDGPPLLPDEARIAKASKNLLKRSNPVFNLHR--PSSKINMVIQILKTSILKSSDDKAIVVSQW 917
                               :..::...:.:|..  ||:|:.::.:|||.  .....:|.::.:.:
Mosquito  1544 -------------------DWWRQYLQIADLESLFPSNKLWILFEILKH--CNERGEKVLIFTAF 1587

  Fly   918 TSVLDILRDHLSK------------------------DGVATLSLNGTIPVKNRQDIVNEFND-R 957
            .|||:::...::|                        .|.....|:|......|..::..||| :
Mosquito  1588 VSVLNMVEHFMAKIHHQEENPQLSDAYAYSAFKGPWEPGKDYYRLDGKTQKSIRHQMITSFNDPQ 1652

  Fly   958 NNQKRVLLLSLTAGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTV 1022
            |.:.:..|:|..|||.|:||.|||.:::||..|||..:.|...||:|:|||:...:|:.:...|:
Mosquito  1653 NKRTKCFLISAKAGGQGINLTGANRVIILDTSWNPSNDQQNIFRIFRLGQKRKCYVYRLIAAGTM 1717

  Fly  1023 EQRIKGLQDKKLDLADGVLTGAKVSSKLTIDDLKGLF 1059
            |:::......|..|:..|:...::....:..:|..|:
Mosquito  1718 EEKVYSRSVTKQALSFRVVDEQQIDRHYSYGELAELY 1754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	176/856 (21%)
		DEXHc_TTF2	439..686	CDD:350830	62/292 (21%)
LOC1271255	XP_061510596.1	None