Protein Alignment lds and chd6

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_004918574.2
• Gene: chd6 / 100498254
• XenbaseID: XB-GENE-5964535
• Length: 2667
• Species: Xenopus tropicalis
• Alignment Length: 1142
• Identity: 245/1142 - (21%)
• Similarity: 411/1142 - (35%)
• Gaps: 396/1142 - (34%)

  Fly     4 ENSEYYSDKEEDSVVNNSSLGRSRK---------------SSRLSKSSRLSKSSRPSSAGVVIDE 53
            |.||....||:....:.....:.||               |:..:|..:|||...|:.    :::
 Frog   128 EPSEAKDPKEQKQPKSPKEPKKPRKPREPKPPKQKKANQDSAAKTKPKKLSKEQGPTP----LEK 188

  Fly    54 TQSEEEESQ-SSETAESEKSDESDNSQNSQESEDSEDDSVRPSARNTKRKPLGIPSDSEDEEDEL 117
            .:..:.::: |.|:.:.|.|..:..||:::||.:|.|...|.|.|..||:..         .::|
 Frog   189 KKKGKRKAEFSEESLDGEPSLLNPASQSTEESTESLDSQKRRSGRQVKRRKY---------NEDL 244

  Fly   118 EQRALSPSTRMSITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPRYTTQFAGNIQNDLHS 182
            :.:.:                 |||.|                                   ..:
 Frog   245 DFKVV-----------------DDDGE-----------------------------------TIA 257

  Fly   183 TIGAADSEVLDDSSGSDVLILSNKETPIEILSSTDDDAT----------TNKENM-SGPPFERPS 236
            .:||..:..|..|:    |....:|.|       :|||.          :.||.| :|.|.|...
 Frog   258 VLGAGRASALSAST----LAWQAEEPP-------EDDANIIERILSSRISQKEFMHAGIPLEVEE 311

  Fly   237 -----KSLSPRSSAGASVVKTSKNLSQPTIQAVLKQKTSPAAPRRSRIKSEDQKVVSQVVYDEEM 296
                 ::.|......|::.:..|:   |.||..:|:..:..| :...|.:|..:.:....|.|..
 Frog   312 FYVKYRNFSYLHCKWATLEELEKD---PRIQQKIKRFRNKQA-QMKHIFTEPDEDMFNPDYVEVD 372

  Fly   297 RKLAEKRVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRRELAMDEQWISALRVQQS------NV 355
            |.|.....:.||..::.| |.|.|                     .:|.| |..::|      :|
 Frog   373 RVLEVAHTKDSDTGEVRE-VTHFL---------------------VKWCS-LPYEESTWELEEDV 414

  Fly   356 PAVRVVK-------PTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMATFNNQKALTLESLK 413
            ..|:|.:       |.|.|...|:.:|  |.:|..:              .|:.|..
 Frog   415 DPVKVKEFEALQKVPDLTPMERPASET--WQKLVSS--------------RTYKNNN-------- 455

  Fly   414 DLHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWM--SWRERKLPRGGILADDMGLGKT---L 473
                                    .|..:|...:.|:  :|..||   ..||||:||||||   :
 Frog   456 ------------------------QLREYQLEGMNWLLFNWYNRK---NCILADEMGLGKTIQSI 493

  Fly   474 TMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRGGTLVVCPASLLRQ 538
            |.:|.:...                                       ..||..|::.|.|.:..
 Frog   494 TFLSEIFFM---------------------------------------GIRGPFLIIAPLSTITN 519

  Fly   539 WESEVESKVSRQKLTVCVHHGNNRETK-----GKYLRD-----------YDIVVTTYQIVAREHK 587
            ||.|..:..   ::...|:||:....:     ..|.||           :.||:||::::..:..
 Frog   520 WEREFRTWT---EMNTIVYHGSQISRQMIHQYEMYYRDEQGTPIPGIYKFQIVITTFEMILADCP 581

  Fly   588 SLSAVFGVKWRRIILDEAHVV--RNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYALLKFLR 650
            .|..   ::|..:|:||||.:  ||.|....|.:..|  :::..|||||:||...::|:||.||.
 Frog   582 ELKK---IRWSCVIIDEAHRLKNRNCKLLEGLKLMAL--EHKVLLTGTPLQNSVEELYSLLNFLE 641

  Fly   651 CSPFDDLHTW-KKWIDNKSAGGQNRLNLLMKSLMLRRTKAQLQSDGKLNSLPNKELRLIEISLDK 714
            ...|....|: :::.|.|:.....:|..::|.:||||    |:.|.:.|..|.:| .:||:.|..
 Frog   642 PVQFPSESTFLEEFGDLKTEEQVKKLQSILKPMMLRR----LKDDVEKNLAPKQE-TIIEVELTN 701

  Fly   715 EEMNVYQTVMTYSRTLFAQFLHQRAERETDFNYRSDANKPTYNQIKDPNGAYYKMHEKFARMAGS 779
            .:...|:.::..:.|    ||.:.|                 ||...||
 Frog   702 IQKKYYRAILEKNFT----FLTKGA-----------------NQHNMPN---------------- 729

  Fly   780 KKEVKSHDILVLLLRLRQICCHPGLIDAMLDGEESQTMGD----HSSDSDTPEIDLLAQ-LNKLA 839
                    ::..::.||:.|.||.||    :|.|.:.:.|    ||.|:...::..:.| ..||.
 Frog   730 --------LINTMMELRKCCNHPYLI----NGAEEKILEDFRKRHSPDALDFQLQAMIQAAGKLV 782

  Fly   840 ITDTSTDGQQSVANAGDDGPPLLPDEARIAKASKNLLKRSNPVFNLHRPSSKINMVIQILKTSIL 904
            :.|                 .|||.                                       |
 Frog   783 LID-----------------KLLPK---------------------------------------L 791

  Fly   905 KSSDDKAIVVSQWTSVLDILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLT 969
            .:...|.::.||....||||.|:|.:.......::|.:....||..::.|...::.:.|.||...
 Frog   792 IAGGHKVLIFSQMVRCLDILEDYLIQRRYIYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTR 856

  Fly   970 AGGVGLNLIGANHLLLLDLHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKL 1034
            |||:|:||..|:..::.|..||||.:.|||.|.:|:||.|.|.:|:.:..::.|:.:......||
 Frog   857 AGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKL 921

  Fly  1035 DLADGVL---------TGAKVSSKLTIDDL--KGLFG 1060
            .|...||         .|.:..||:.::||  ||.:|
 Frog   922 GLDKAVLQDINRKGNTNGVQPLSKIEVEDLLRKGAYG 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	176/795 (22%)
		DEXHc_TTF2	439..686	CDD:350830	68/270 (25%)
chd6	XP_004918574.2	CD1_tandem_CHD5-9_like	281..347	CDD:349315	16/68 (24%)
		CD2_tandem_CHD5-9_like	366..426	CDD:349310	17/82 (21%)
		PLN03142	456..>981	CDD:215601	160/663 (24%)
		DEXHc_CHD6	457..678	CDD:350816	68/270 (25%)