Protein Alignment lds and ino80

DIOPT Version :10

• Sequence 1: NP_524850.2
• Gene: lds / 45894
• FlyBaseID: FBgn0002542
• Length: 1061
• Species: Drosophila melanogaster
• Sequence 2: XP_004917366.1
• Gene: ino80 / 100127778
• XenbaseID: XB-GENE-957629
• Length: 1547
• Species: Xenopus tropicalis
• Alignment Length: 1311
• Identity: 272/1311 - (20%)
• Similarity: 464/1311 - (35%)
• Gaps: 418/1311 - (31%)

  Fly    13 EEDSVVNNSSLGRSRKSSRLSKSSRLSKSSRPSSAGVVIDETQSEEEESQSSETAES-------E 70
            |..|..|.|.|.:|||   ..|:..||:.|..:       ::.|||:|.:.|.:.|.       .
 Frog   108 ERGSFYNFSKLKKSRK---WLKNILLSEDSSDT-------DSLSEEDEEEFSLSKEELHDMLRIH 162

  Fly    71 KSDESDNSQNSQESEDSEDDSVRPSARNT-------KRKPLGIPSDSEDEEDELEQRALSPSTRM 128
            |..:...|:..::.|..:.........:|       :|..||.......||.:.:.:......:.
 Frog   163 KYKKLHQSKYLKDKELHQYQYYSAGLLSTHDPFYEQQRHFLGPRKKKIKEEKKFKAKLKKVKKKR 227

  Fly   129 SITGVRPQDLSDDDSEIEYSDEVQEGPTEAPTAEAVVPR---YTTQFAGNIQNDLHSTIGAADSE 190
            .    |.:|||:|:                      :||   :|..|| ...:|..:.:|.....
 Frog   228 R----REEDLSEDE----------------------LPRRHHHTKVFA-KFSHDAPTPVGKKKHL 265

  Fly   191 VLDDSSGSDVLI---LSNKETPIEILSSTDDDATTNKENMSGPPFERPSKSLSPRSSAGASVVKT 252
            .|:..:.....:   :..||.|                           |:...:.||...::..
 Frog   266 TLEQLNARRRKVWQMIVKKELP---------------------------KAYKQKVSARNLLLTN 303

  Fly   253 SKNLSQPTIQ-----AVLKQKT-SPAAPRRSRIKSE-------------------DQKVVSQVVY 292
            ||.|:...::     |:..||. ....||..|:..|                   :::.:.|...
 Frog   304 SKKLAHQCMREVRRAAIQAQKNCKETLPRARRLTKEMSLYWKKYDKVEKEHRKRAEKEALEQRKL 368

  Fly   293 DEEMRKLAEK-------------------RVQVSDAEKLFEKVAHKLPDKGSQIMKRIDTLRREL 338
            |||||:...:                   |.:.|..:.:.|::..||.|..||         .::
 Frog   369 DEEMREAKRQQRKLNFLITQTELYAHFVSRKRESGPDGIQEEILRKLEDSSSQ---------EQV 424

  Fly   339 AMDEQWISALRVQ-QSNVPAVRVVKPTLNPPRAPSIDTLDWDELSEAVNEIKPVYTGAQGMAT-- 400
            .....::...::. .|:....:.:|......|.....|..:||      :.|.....||.:|.
 Frog   425 GAGGSYLHLSQMDYDSDYYKSQALKNAEEAFRIHQAQTRSFDE------DAKESRAAAQRVAIKL 483

  Fly   401 ---FNNQKALTLESLKDLHVSLEDLPGPEVLAEDPVGLKVSLMNHQKHALAWMSWRERKLPRG-- 460
               |....:|...|::    :.||:|.|.:       ....|..:|   |..|:|......:|
 Frog   484 ESGFGESYSLANPSIR----AGEDIPQPTI-------FNGKLKGYQ---LKGMNWLANLYEQGIN 534

  Fly   461 GILADDMGLGKTLTMISSVLACKNGQEMSEGKDESSDSDSEDDKNKKRKSVTGWKSKGRKDTRRG 525
            |||||:||||||:..| ::||     .::|                 |:::  |          |
 Frog   535 GILADEMGLGKTVQSI-ALLA-----HLAE-----------------RENI--W----------G 564

  Fly   526 GTLVVCPASLLRQWESEVESKVSRQKLTVCVHHGNNRETK------GK---YLRD--YDIVVTTY 579
            ..|::.|||.|..|..|....|  .|..|..:.|:..|.|      |:   |.::  :.:|:|:|
 Frog   565 PFLIISPASTLNNWHQEFSRFV--PKFKVLPYWGSPHERKVIRKFWGQKTLYTQEAPFHVVITSY 627

  Fly   580 QIVAREHKSLSAVFGVKWRRIILDEAHVVRNHKSQSSLAVCDLRGKYRWALTGTPIQNKELDVYA 644
            |:|.::.|....   |||:.::||||..:::..|.....:...:.:.|..||||||||...:::|
 Frog   628 QLVVQDVKYFQR---VKWQYMVLDEAQALKSSSSVRWKILLQFQCRNRLLLTGTPIQNTMAELWA 689

  Fly   645 LLKFLRCSPFDDLHTWKKWI--------DNKSAGGQN---RLNLLMKSLMLRRTKAQLQSDGKLN 698
            ||.|:..:.||....:.:|.        :||||..:|   ||::::|..||||.|..::     |
 Frog   690 LLHFIMPTLFDSHDEFSEWFSKDIESHAENKSAIDENQLSRLHMILKPFMLRRIKKDVE-----N 749

  Fly   699 SLPNKELRLIEISLDKEEMNVYQT-------------------------------VMTYSRTLFA 732
            .|.:|...|:..||...:..:||.                               ||.:.:....
 Frog   750 ELSDKIEILMYCSLTTRQKLLYQALKNKISIDDLLQSSMGTAQQAQNTTSSLMNLVMQFRKVCNH 814

  Fly   733 QFLHQRAERETDFNY-------------RSDANKPTYNQ------IKDPNGAYYKMHEKFARMAG 778
            ..|.:|.|..:.|::             ..:.|...:::      :..|....:.....|.|...
 Frog   815 SELFERQETWSPFHFSLRPYQISKFLFRHGNINCLNWSRNRWLRVMLSPFAPDHIQQSLFHRNGS 879

  Fly   779 SKKEVKSHDILVLLLRLRQICCHPGLI-DAMLDGEESQTMG-----------------DHSSDSD 825
            .|:...|      .||...:|  |..| :.||.|..::.:.                 |..|.||
 Frog   880 DKESCFS------FLRFIDVC--PAEIGNLMLRGHLARWLALFLSLKAAYRLHNARVWDEGSQSD 936

  Fly   826 T--------------------PEIDLLAQLNKLAIT----------------------------- 841
            :                    |.:...:.|.:|..|
 Frog   937 SLNSYLTNRSLILWVNFALSFPNLHSSSTLQELVFTSHCRPISGRGDYVLHGRKSGQSQVLHCQI 1001

  Fly   842 ------------------------DTSTDGQQSVANAGD----------DGPPLLPD----EARI 868
                                    |.|.:.::.....|.          ..|.|..|    :.:.
 Frog  1002 TQFPSFLYVASPLVTASPIDIYCNDRSAEYERREFREGGGPVSRQCLMFGAPELYADWPKRQLQF 1066

  Fly   869 AKASKNLLKRSNPV-----------FNLHRPSSKINMVIQILKTSILKSSDDKAIVVSQWTSVLD 922
            ..||...|....|.           .:|...|.|: ..:.:|.|. |||...:.::.||.|.::|
 Frog  1067 FPASPGGLMTIKPCNGWSYIKIPDKESLITDSGKL-YALDLLLTR-LKSHGHRVLIYSQMTRMID 1129

  Fly   923 ILRDHLSKDGVATLSLNGTIPVKNRQDIVNEFNDRNNQKRVLLLSLTAGGVGLNLIGANHLLLLD 987
            :|.:::.......:.|:|:..:..|:|:|.:|..|.: ..|.|||..|||:|:||..|:.::..|
 Frog  1130 LLEEYMVYRKHTYMRLDGSSKISERRDMVADFQSRTD-IFVFLLSTRAGGLGINLTAADTVIFYD 1193

  Fly   988 LHWNPQLEAQAQDRIYRVGQKKNVIIYKFMCVDTVEQRIKGLQDKKLDLADGVLTGA-------- 1044
            ..|||.::.||.||.:|:||.|.|.:|:.:|..|:|:||.....:|.::...|::|.
 Frog  1194 SDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRVVISGGNFKPDTLK 1258

  Fly  1045 -KVSSKLTIDD 1054
             |....|.:||
 Frog  1259 PKEVVSLLLDD 1269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lds	NP_524850.2	HepA	287..1041	CDD:440319	210/968 (22%)
		DEXHc_TTF2	439..686	CDD:350830	79/270 (29%)
ino80	XP_004917366.1	HepA	330..>826	CDD:440319	130/569 (23%)
		DEXQc_INO80	514..742	CDD:350760	79/270 (29%)
		SF2_C_SNF	1088..1223	CDD:350180	45/137 (33%)