Protein Alignment kkv and HAS3

DIOPT Version :10

• Sequence 1: NP_524233.1
• Gene: kkv / 45884
• FlyBaseID: FBgn0001311
• Length: 1615
• Species: Drosophila melanogaster
• Sequence 2: NP_005320.2
• Gene: HAS3 / 3038
• HGNCID: 4820
• Length: 553
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 98/472 - (20%)
• Similarity: 177/472 - (37%)
• Gaps: 117/472 - (24%)

  Fly   683 TPYGGRLVWTL------PGKTKFITHLKD-KDRIRH----------RKRWS---QVMY-MYYLLG 726
            |...|..||..      .|:|:  ..|:: .||:|.          .::|.   :||| .:..||
Human   143 TEQAGFFVWRSNFHEAGEGETE--ASLQEGMDRVRDVVRASTFSCIMQKWGGKREVMYTAFKALG 205

  Fly   727 HRLMELPISVDRKDAIAENTYLLTLDGDIDFKPNAVTLLVDLMKKNKNLGAACGRIHPVGSGPMV 791
            .       |||         |:...|.|....|.....::.:::::..:|...|.:..:.....
Human   206 D-------SVD---------YIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQILNKYDS- 253

  Fly   792 WYQLFEYAIGHWL----QKATEHMIGCVLCSPGCFSLFRGKAL---MDDNVMKKYTTRSDEARHY 849
            |.. |..::.:|:    ::|.:...|||.|..|...::|...|   ::|...:|:...
Human   254 WIS-FLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFLGS------- 310

  Fly   850 VQYDQGEDRWLCTLLLQRGYRVEYSAASDAYTHCPEGFNEFYNQRRRWVPSTIAN-IMDLLADAK 913
             :...|:||.|...:|..|||.:|:|.|...|..|..:..:.||:.||..|.... :.:.|...|
Human   311 -KCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYNSLWFHK 374

  Fly   914 RTIKINDNISLLYIFYQMMLMGGTILGPGTIF-LMLVGAFVAAF---RIDNWTSF--HYNIVPIL 972
            ..         |::.|:.::.|        .| ..|:...:..|   ||.|...|  ...:|.|:
Human   375 HH---------LWMTYESVVTG--------FFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGII 422

  Fly   973 AFMFICFTCKSNIQLFVAQVLSTAYALIMMAVIVGTALQLGEDGIGS--------------PSAI 1023
            ...:.|| .:.|.::....:.|..|...::...:.....:.:.|.|:              |.:|
Human   423 KATYACF-LRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSI 486

  Fly  1024 FLISMVGSF-FIAACLHPQEFWCITCGLIYLLSIPSMY-----LLLILYSIINLNVVSWGTREVV 1082
            ::..::|.. :.|.|   |:.:..| .|.:|:|...:|     .||:||..|            :
Human   487 WVAVLLGGLAYTAYC---QDLFSET-ELAFLVSGAILYGCYWVALLMLYLAI------------I 535

  Fly  1083 AKKTKKELEAEKKAAEE 1099
            |::..|:.|....|..|
Human   536 ARRCGKKPEQYSLAFAE 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kkv	NP_524233.1	Chitin_synth_C	583..904	CDD:133033	56/248 (23%)
HAS3	NP_005320.2	GT2_HAS	86..364	CDD:133056	56/248 (23%)