Protein Alignment kar and SLC16A7

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_011537291.1
• Gene: SLC16A7 / 9194
• HGNCID: 10928
• Length: 504
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 114/472 - (24%)
• Similarity: 198/472 - (41%)
• Gaps: 63/472 - (13%)

  Fly    63 PCCRDIHGKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGV----IHSLLTDRLTKLGDPEASSK 123
            |....:|  .||||| ..|:|:.:||:..|..:.|.....|    |..:.....:::....:...
Human     5 PSAPPVH--PPPDGG-WGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIML 66

  Fly   124 AALIGALAIGTTFL----------FSTMAGC-------LTDKIGLRLTTFAGGVLSAGGLLLSSF 171
            |.:.....|..:||          |:....|       |.:|.|.|....|||:|...|::|:||
Human    67 AVMYAGGRIFESFLIFTSLRIQCSFTQSGSCLGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASF 131

  Fly   172 CTENIGALYFTYGIMFGLGAALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLL 236
             :.::..||.|.|.:.|||.|....|.|.|:|.||.|.....:|...|||.||...|.|....|.
Human   132 -SSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLF 195

  Fly   237 GSYGLEGTLRIMSLVSAFIILCSFVYKPLHP-------------------PPEPPKKKPGRSRIN 282
            .::|.:|:..|:..:.....:...:.:||.|                   |.:...||....::|
Human   196 NTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVN 260

  Fly   283 LFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTTFPGEDVNLPVMCIGITSGI- 346
            .:|    :..::|.:.|:|:.....:...|:|.|.:.:..:.|.  .|.|.......:.:.:.:
Human   261 KYL----DFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKD--QGIDEYSAAFLLSVMAFVD 319

  Fly   347 --GRLIFGVIADMPGVNR--MYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLL 407
              .|...|:||:...:..  .|....:::..|:..||.||...|..||.:.:..||..|...|:|
Human   320 MFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVL 384

  Fly   408 GPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYTLP-------LILAGLPPLL 465
            .....::.|....:.|:|.:..:...|:.:|||:||.:.|.|..|...       ::.|.:..|:
Human   385 FETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLI 449

  Fly   466 GSSLLF-LIKCVKEEEN 481
            |:::.: |:...::|||
Human   450 GNAINYRLLAKERKEEN 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	104/446 (23%)
SLC16A7	XP_011537291.1	2A0113	15..484	CDD:273325	110/460 (24%)