Protein Alignment kar and SLC16A6

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_005257846.2
• Gene: SLC16A6 / 9120
• HGNCID: 10927
• Length: 527
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 114/528 - (21%)
• Similarity: 203/528 - (38%)
• Gaps: 126/528 - (23%)

  Fly    72 EPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            |.|||| ..|.|.||.|......:|.|.|:||..:.|.|...     |::|:.:.|.::.:....
Human    21 EVPDGG-WGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFN-----ESNSRISWIISICVFVLT 79

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            ..:.:|..|:::.|.||....||:|.:.|::.:|| ::.:..:|...||:.|||...::.||:.|
Human    80 FSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASF-SQEVSHMYVAIGIISGLGYCFSFLPTVTI 143

  Fly   202 LGHYFKRYLGKVSGFVTAGSSV---FTVI-LPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVY 262
            |..||    ||....|||.:|.   |.|. ..|.:..|....|...:|..:.|:...|::...:.
Human   144 LSQYF----GKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALL 204

  Fly   263 KP--LHPPPEP------------------------------------PKKKPGRSRINLFLRS-- 287
            :|  :..|..|                                    ||..|..:.:.|..::
Human   205 RPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADM 269

  Fly   288 -----------------IINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTTFPGEDVNL 335
                             :::..|.|.|.|:.:||....|..|:|.|                 :|
Human   270 QQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAP-----------------SL 317

  Fly   336 PVMCIGITSGI------------------GRLIFGVIADMPGVNRMYLQQLSLVSIGLVTLLLPL 382
            .::.:||:.||                  ||:..|.:.:...:.::|::.:.::.:.:.......
Human   318 YIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTF 382

  Fly   383 TNSYVILVS----FTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAG 443
            ...:..|:|    |..::|...|..|.||.  ..::.|....:.|.|..:.:.||....|||:||
Human   383 ATEFWGLMSCSIFFGFMVGTIGGTHIPLLA--EDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAG 445

  Fly   444 MIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVK--------EEENGVSAPRAVVLAN-----GD 495
            ::.|.:..|:...........|.:..|.|::..|        ..|..|.:.|...|.:     .:
Human   446 LLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLE 510

  Fly   496 IEIAGNGH 503
            :::|.|.|
Human   511 MDLAKNEH 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	98/460 (21%)
		MFS_1	124..439	CDD:284993	77/397 (19%)
SLC16A6	XP_005257846.2	2A0113	23..512	CDD:273325	110/518 (21%)
		MFS	33..476	CDD:119392	99/471 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810