Protein Alignment kar and MCH5

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_014951.4
• Gene: MCH5 / 854483
• SGDID: S000005833
• Length: 521
• Species: Saccharomyces cerevisiae
• Alignment Length: 449
• Identity: 117/449 - (26%)
• Similarity: 182/449 - (40%)
• Gaps: 80/449 - (17%)

  Fly    74 PDGGARAWLVMVSAFLCNGII--FGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            |:||.:||:|....||  |:|  ||.:|:.|||.|.|.|      :..:|...:.||.|.  :.|
Yeast   100 PEGGFKAWVVTFGCFL--GLIACFGLLNSTGVIESHLQD------NQLSSESVSTIGWLF--SLF 154

  Fly   137 LFSTMAGCLT-----DKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALY---FTYGIMFGLGAAL 193
            ||...|.|:.     |:.|.|.....|.|....||    |.|.|....:   .::.|:.|.|..:
Yeast   155 LFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGL----FATANSTKYWHFILSFAIVCGFGNGI 215

  Fly   194 AYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLG-------SYGLEGTLRIMSLV 251
            ..:|.:::..|||.:..|......|.|.||..|:.|..|.....       :||....:|.:..:
Yeast   216 VLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFL 280

  Fly   252 SAFIILCSFVYKPLHPPPEPPKKKPGRSRINLFLRSIINVEIWKRKRF--VIWALCVPLALFG-- 312
            ...::..|.:......|......|.|.||....||..| ::.:..|.|  :.:..||...:|.
Yeast   281 DLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYI-LQCFDAKAFLDMKYLFCVLGTVFSEL 344

  Fly   313 -------YFVPYVHMMQFVKTTFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSL 370
                   |:..|.     ........|....:|.|.:....||.:.|.::|..|  |..:...:|
Yeast   345 SINSALTYYGSYA-----TSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFG--RFNVAIATL 402

  Fly   371 VSIGLVTLL--LP----LTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIG---- 425
            :::.:|..:  ||    |||.|||    :.:.|...|...||| |:.   ||....|:..|
Yeast   403 LTLFIVMFVGWLPFGTNLTNMYVI----SALYGFCSGSVFSLL-PVC---CGQISKTEEFGKRYS 459

  Fly   426 ---FLLGLSSIPLTVGPPVAGMIFD--STNSYTLPLILAGLPPLLGSSLLFLIK---CV 476
               |::|..::   ||.|:.|.|..  :|..|...:|..||...: |::.::|.   ||
Yeast   460 TMYFVVGFGTL---VGIPITGAIISIKTTADYQHYIIFCGLATFV-SAVCYIISRAYCV 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	111/436 (25%)
MCH5	NP_014951.4	MFS_MCT_SLC16	106..510	CDD:340910	112/437 (26%)