Protein Alignment kar and MCH4

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_014522.1
• Gene: MCH4 / 854030
• SGDID: S000005479
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 418
• Identity: 104/418 - (24%)
• Similarity: 182/418 - (43%)
• Gaps: 50/418 - (11%)

  Fly    71 KEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLT-DRLTKLGDPEASSKAALIGALAIGT 134
            :|.||||.:||||:..||:....:||.||:.|.|.|.:: .:|..:    :||..:.|.:|.:..
Yeast    87 REFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANI----SSSTISWIFSLYLAI 147

  Fly   135 TFLFSTMAGCLTDK---IGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYT 196
            :||...::|...|:   |||..|   |.|:.||||...:.| :::......:.:..|||..:..|
Yeast   148 SFLSCILSGGYFDRNGSIGLMCT---GTVIYAGGLFALANC-KSVWQFILAFSVCSGLGTGILMT 208

  Fly   197 PTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFV 261
            |.:..:..:|.:..|..:...|.|.|:..::.|..|.||....|.:..:||:|.:....::|:.|
Yeast   209 PLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASV 273

  Fly   262 YKPLHPPPEPPKKKPGRSRINL---FLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQF 323
               |......|..:|.:|:..:   ::.|:.|...:...:|:..|:....|.........::..:
Yeast   274 ---LARERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASY 335

  Fly   324 VKTTFPGEDVNLPVMCIGITSGI-GRLIFGVIAD-MPGVNRMYLQQLSLVSIGLVTLLLPLTNSY 386
            ..|....|:|...::......|| ||.|.|..|| ..|...:.:..:|:.::....:.||...:.
Yeast   336 SMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNT 400

  Fly   387 VILVSFTLVMGLFDGCFISLLGPIAYEIC-GPSGATQAIG-------FLLGLSSIP-LTVGPPVA 442
            .:|.::..:.|...|..:||.     .:| |....|...|       .|..|.:|| |.:|..:.
Yeast   401 KVLWAYVCLWGFSTGSILSLT-----PVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLI 460

  Fly   443 G----------MIFDSTNSYTLPLILAG 460
            |          :||:|.      |:.||
Yeast   461 GKGTVANYNHFIIFNSA------LMAAG 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	99/409 (24%)
MCH4	NP_014522.1	MFS_MCT_SLC16	96..490	CDD:340910	99/409 (24%)