Protein Alignment kar and ATG22

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_009892.1
• Gene: ATG22 / 850319
• SGDID: S000000543
• Length: 528
• Species: Saccharomyces cerevisiae
• Alignment Length: 483
• Identity: 72/483 - (14%)
• Similarity: 145/483 - (30%)
• Gaps: 235/483 - (48%)

  Fly   101 YGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLS-AG 164
            :|::.:|.|..::||.|.:..|.|.           |:....||.             ||:: .|
Yeast   135 FGIVGALSTVAISKLNDTQIYSLAG-----------LYIVANGCF-------------GVINVVG 175

  Fly   165 GLLLSSFCTENI-----GALYFTY---------GIMFGLGAALAYTPTLAILGHYFKRYLGKVSG 215
            ..||..|..:::     ||    |         .::.|.||:|.|:..|
Yeast   176 NSLLPIFVKDSLKCQSQGA----YEPDKVDSLTTVISGRGASLGYSSAL---------------- 220

  Fly   216 FVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLHPPPEPPKKKPGRSR 280
                                           |:.:||.|::               ..||..:..
Yeast   221 -------------------------------IVQIVSMFLV---------------ASKKGSKQD 239

  Fly   281 INLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFV--------------KTTFPGE 331
            :.:   :::.|.||    :.:|.|           |.:.::..|              ::.:|||
Yeast   240 VQV---AVLFVGIW----WFVWQL-----------PMIWLIDDVTIPIRVDDSTLASARSPYPGE 286

  Fly   332 DVNLPVMCIGITSGIGRLIFG-------------------------VIAD-MPGVN--------- 361
            .     ..:|..:....|.:|                         :|:| :..:|
Yeast   287 Q-----DALGQLNWKNYLSYGWVSLFESFKHARLLKDVMIFLIAWFIISDSITTINSTAVLFSKA 346

  Fly   362 RMYLQQLSLVSIGLVTLLLPLTNSYVI------------------------LVSFTLVMGLFDGC 402
            .:::..|:|:.|.::|::..:..:::|                        .:.|..::|.|...
Yeast   347 ELHMSTLNLIMISVLTVVNAMLGAFMIPQFLATKFRWTSSQTLMYIIIWASFIPFYGILGFFFNA 411

  Fly   403 F---------------------ISLLGPIAYEICGPSGATQAIGFLLGL----SSIPLTVGPPVA 442
            |                     :|.:....:.:..|.|.......:..:    |||   :||.:.
Yeast   412 FGLKHKFEMFLLAIWYGLSLGGLSAVSRSVFSLIVPPGKESTFFSMFSITDKGSSI---LGPFLV 473

  Fly   443 GMIFDSTNS------YTLPLILAGLPPL 464
            |::.|.|::      :...|::..||.|
Yeast   474 GLLTDKTHNIRYSFYFFFLLLMLSLPVL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	72/483 (15%)
ATG22	NP_009892.1	MFS_Atg22_like	28..484	CDD:341036	68/464 (15%)