Protein Alignment kar and Slc16a3

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_110461.1
• Gene: Slc16a3 / 80878
• RGDID: 620603
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 444
• Identity: 117/444 - (26%)
• Similarity: 200/444 - (45%)
• Gaps: 51/444 - (11%)

  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGT 134
            |.:.|||| ..|.|:...|:..|..:.|.....|....|.... .:|..:.:..::::.|:..||
  Rat    12 GIKAPDGG-WGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEF-GIGYSDTAWISSILLAMLYGT 74

  Fly   135 TFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTL 199
            ..|.|.   |: ::.|.|.....||:.::.|::.:||| .:|..:|.|.|::.|||.||.:.|:|
  Rat    75 GPLCSM---CV-NRFGCRPVMLVGGLFASLGMVAASFC-RSIIQIYLTTGVITGLGLALNFQPSL 134

  Fly   200 AILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKP 264
            .:|..||.:.....:|...|||.||...|.|....|...||..|...|:..:.....:|:.:.:|
  Rat   135 IMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRP 199

  Fly   265 LHPP-------PEPPKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQ 322
            |..|       |..|::...|         ::::.:::.:.|:|:|:...:.:.|.|||.|.::.
  Rat   200 LVAPQASGGAEPHGPQRPSPR---------LLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVS 255

  Fly   323 FVKTTFPGEDVNLP-------VMCIGITSGIGRLIFGVIADMPGVN--RMYLQQLSLVSIGLVTL 378
            :.|      |:.:|       :..:|......|...|.|..:..|.  .:||...::...|...|
  Rat   256 YAK------DMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDL 314

  Fly   379 LLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYE----ICGPSGATQAIGFLLGLSSIPLTVGP 439
            .....:.|..||.|.:..|:..|    ::|.:.:|    |.|....:.|||.:|.|.::.:.:||
  Rat   315 TGSTASDYGGLVVFCIFFGISYG----MVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGP 375

  Fly   440 PVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIK---CV-KEEENGVSAPRAV 489
            |..|.:.|:|..|....|||| ..:|.|||:.|:.   |: |.:...|:.|..|
  Rat   376 PSGGKLLDATKVYKYVFILAG-AEVLTSSLVLLLGNFFCIGKRKRPEVTKPEEV 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	99/397 (25%)
		MFS_1	124..439	CDD:284993	83/334 (25%)
Slc16a3	NP_110461.1	MFS_MCT3_4	21..410	CDD:340988	107/414 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820