Protein Alignment kar and Slc16a13

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_758959.1
• Gene: Slc16a13 / 69309
• MGIID: 1916559
• Length: 428
• Species: Mus musculus
• Alignment Length: 441
• Identity: 119/441 - (26%)
• Similarity: 206/441 - (46%)
• Gaps: 43/441 - (9%)

  Fly    72 EPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            |||||| ..|:|::|||..:.::||.:.::||.........     .|.:::.:.|.::.|....
Mouse     6 EPPDGG-WGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAF-----EEQAARVSWIASIGIAVQQ 64

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            ..|.:...|:.|:|.|.....||:|:|.|:||:||.| ::..||.:.|::.|.|.||.:|||:|.
Mouse    65 FGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFAT-SLTHLYLSIGLLSGSGWALTFTPTMAC 128

  Fly   202 LGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLH 266
            |..||.:......|....|..:.:....|....|:.:|...|.|.::|.:|..::.|..:.:||.
Mouse   129 LSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLS 193

  Fly   267 PPPEPPKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTTFPGE 331
            ...:.....|| ::|...||         ...|:.:...:.|...|:|:||||::..::..  |.
Mouse   194 LTEDAAVGGPG-AQITSLLR---------HGPFLRYTAALTLINTGFFIPYVHLVAHLQDL--GW 246

  Fly   332 DVNLPVMCI----GITSGIGRLIFGVIAD-MPG-VNRMYLQQLSLVSIGLVTLLLPLTNSYVILV 390
            | .||...:    .::..:||:..|.:.| :|| |.|:.:...:|..:.|.  |.|:..:...||
Mouse   247 D-PLPAAFLLSVAAVSDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLA--LFPVAQASSTLV 308

  Fly   391 SFTLVMGLFDGCFISLLGPIAY----EICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNS 451
            ...:..|...|.    |.|:|:    |:.|.......:|.:..:.||...:|.|::|.:.|.|.:
Mouse   309 VLAVAYGFTSGA----LTPVAFSVLPELVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGN 369

  Fly   452 YTLPLILAGLPPLLGSSLLFLI----KCVKEEENGVSAPRAVVLANGDIEI 498
            ||...::||...|.||.:|..:    .|:..   ..|.|:.:|:...|.:|
Mouse   370 YTASFVVAGAFLLAGSGVLLTLPHFFSCISV---STSRPQDLVIEASDTKI 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	107/407 (26%)
Slc16a13	NP_758959.1	MFS_MCT11_13	13..392	CDD:340981	107/403 (27%)