Protein Alignment kar and Slc16a5

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001103038.1
• Gene: Slc16a5 / 690212
• RGDID: 1582896
• Length: 466
• Species: Rattus norvegicus
• Alignment Length: 462
• Identity: 106/462 - (22%)
• Similarity: 205/462 - (44%)
• Gaps: 44/462 - (9%)

  Fly    77 GARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGA-LAIGTTFLFST 140
            |..||:|::::.:...:..||.:..||..:.| .|..:..:.|.|...:::|| |..|     ..
  Rat    10 GRWAWVVLLASLVTQALTVGFPSCIGVFFTDL-QRDFQASNSETSWFPSIMGAMLHCG-----GP 68

  Fly   141 MAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAILGHY 205
            :...|..:.|.|:|...||||::.|::.|:| ::::..|:.|.|::.|||...::..::.::|.|
  Rat    69 LCSILIKRFGCRVTMMLGGVLASLGMVASTF-SDSLIHLFLTAGLITGLGMCFSFQSSITVVGLY 132

  Fly   206 FKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPL--HPP 268
            |.|.....:...:.|.|:...:.|.....||.:.|..|...|...:.....:|..:.:|:  :..
  Rat   133 FVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVD 197

  Fly   269 PEP------PKKKPGRSRINLFLRSI---INVEIWKRKR-FVIWALCVPLALFGYFVPYVHMMQF 323
            |||      |.|.|.||.:...:.:|   :..:|.:... |.|:.........|:.:|::.::.:
  Rat   198 PEPKEDLLLPPKTPTRSCLATCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPY 262

  Fly   324 VKTTFPGEDVNLPVMCI-GITSGIGRLIFGVIADMPGV--NRMYLQQLSLVSIGLVTLLLPLTNS 385
            .......|.....:|.| |..:...|.:.|::|....:  .|.||..::::..||..|:..::..
  Rat   263 AMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAYRKYLFAVAILINGLTNLICTVSAD 327

  Fly   386 YVILVSFTLVMGLFDGCFISLLG------PIAYEICGPSGATQAIG---FLLGLSSIPLTVGPPV 441
            :.:|:.:.||..|      |:.|      .:..:|........|:|   .|.|:.|:   :.||:
  Rat   328 FRVLLGYCLVYSL------SMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSL---ISPPL 383

  Fly   442 AGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEENGVSAPRAVVLANGDIEIAGNGHYRS 506
            ||::.|:||::.....::.  .||.|:.||:.......|..:...|...:.:...||... |..:
  Rat   384 AGLLLDTTNNFNYVFYMSS--GLLISASLFMGVGFYVAEKKLKQDRQAKMEDATSEITSK-HSLT 445

  Fly   507 AGTKSSA 513
            :..|.||
  Rat   446 SEDKDSA 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	97/418 (23%)
Slc16a5	NP_001103038.1	2A0113	1..432	CDD:273325	100/439 (23%)