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Protein Alignment kar and SLC16A2

DIOPT Version :10

Sequence 1:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_006508.2	Gene:	SLC16A2 / 6567	HGNCID:	10923	Length:	539	Species:	Homo sapiens

Alignment Length:	443	Identity:	167/443 - (37%)
Similarity:	272/443 - (61%)	Gaps:	21/443 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGT 134
            |.:||:||. .|:|:.:|..|||.|||..|:.|:::|:|.:. .|..:.:...:||.:||||:|.
Human    91 GFQPPEGGF-GWVVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGM 153

  Fly   135 TFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTL 199
            .|..|.:....||::|.|:|..||..::..||..||| |.::...||||||:||.|.:.|:.|:|
Human   154 IFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSF-TSSLSLRYFTYGILFGCGCSFAFQPSL 217

  Fly   200 AILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKP 264
            .||||||:|.||..:|.|:||||:|::..|..:..|.....|..|.:::|.....::|.|..|:|
Human   218 VILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSLTYRP 282

  Fly   265 LHPPPEPPKKKPG----RSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVK 325
            |.|..:....|.|    ..|....||...|:.:::::.:.|||..:..|..||||||||:|::|:
Human   283 LLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVE 347

  Fly   326 TTFPG-EDVNLPVMCIGITSGIGRLIFGVIAD-MPGVNRMYLQQLSLVSIGLVTLLLPLTNSYVI 388
            ..|.. ::..:.::|||.|||:|||:.|.|:| :||:.::|||.||.:.:||:::::||...:..
Human   348 EEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGG 412

  Fly   389 LVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYT 453
            |:...|.:||.||.||:::.|||:|:.||..|:||||:|||:.::|:..|||:||::.:....|.
Human   413 LIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYH 477

  Fly   454 LPLILAGLPPLLGSSLLFLI-----KCVKEEENGVSAPRAVVLA-----NGDI 496
            :....||:||::|:.:||.:     :..|:|:...|..:  :||     ||::
Human   478 VAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDK--MLAPDPDPNGEL 528

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.