DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kar and zgc:114041

DIOPT Version :9

Sequence 1:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001025143.1	Gene:	zgc:114041 / 574425	ZFINID:	ZDB-GENE-050706-122	Length:	433	Species:	Danio rerio

Alignment Length:	428	Identity:	109/428 - (25%)
Similarity:	202/428 - (47%)	Gaps:	37/428 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 HGKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVI-------HSLLTDRLTKLGDPEASSKAAL 126
            :.::||||| ..|:|:.|||...|:....:..:|:.       :|:||            |..:|
Zfish     4 YSRDPPDGG-YGWVVVASAFFIMGLTAAVLKNFGLFFLELQNYYSVLT------------STTSL 55

  Fly   127 IGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGA 191
            :.:..|....|.|.:|..|:..:..|.....||:|:|.|::::|... ::..:|.:.|::.|||.
Zfish    56 MTSTTIAVFHLGSPLASALSMHLSQRPVIMVGGLLAASGMIIASLGL-SLPWMYLSVGVIQGLGV 119

  Fly   192 ALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFII 256
            :..:.|..:::.|||||:........::|..||.:...|....|:.||...|.|.::..:...:|
Zfish   120 SFTWVPANSMVNHYFKRWRPIACAISSSGECVFGMAFSPFFQWLIESYSWRGALLVIGGLQLNLI 184

  Fly   257 LCSFVYKPLHPPPE------PPKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFV 315
            :|..:.|||.|...      ..|:..|.|:...|..|:|     :|...:::.:....|..|:|:
Zfish   185 VCGALMKPLQPVQTSRKAVLDSKEGTGTSKKVTFQCSLI-----QRPELLLYIVFAIFAAAGFFI 244

  Fly   316 PYVHMMQFVKTTFPGEDVNLPVMCIGITS---GIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVT 377
            |.:.::.:|...  |.|.......:.:.|   .:|||..|.:|::..:..:.|..:...::|:|.
Zfish   245 PPLFLVPYVNNL--GMDQYWAASLLSVLSLADLLGRLGCGWLANLCLLRNLQLLTMVATAMGVVL 307

  Fly   378 LLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVA 442
            ||||:...|..::.||.:.|...||.:::......:|.|..|...|:|..:.|.||...:|||.|
Zfish   308 LLLPIAYGYWSVLVFTSLYGFLFGCVVAIHVTSIVDIVGLEGFDSALGLFMLLRSIGGFLGPPAA 372

  Fly   443 GMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEE 480
            |.:.|.|:::.....|:|:..||....:.|:..:.|::
Zfish   373 GWLVDWTHNFGAAFYLSGICLLLSGCFVVLVDWLVEKK 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	98/393 (25%)
kar	NP_001189213.1	MFS_1	124..439	CDD:284993	80/323 (25%)
zgc:114041	NP_001025143.1	2A0111	15..396	CDD:273323	101/400 (25%)
zgc:114041	NP_001025143.1	MFS	18..403	CDD:119392	100/404 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820