Protein Alignment kar and slc16a12a

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_009291327.2
• Gene: slc16a12a / 557762
• ZFINID: ZDB-GENE-080721-24
• Length: 617
• Species: Danio rerio
• Alignment Length: 628
• Identity: 136/628 - (21%)
• Similarity: 237/628 - (37%)
• Gaps: 182/628 - (28%)

  Fly     1 MAENEPLNDLQSQVNGRILPAANG----HTASATNGLVHANGKDAMKPSAPVQNGNGNANGTHIE 61
            |.|.|.:|..::: .||..||..|    ..|..:.|:     |:.||        .|...... :
Zfish     9 MREKELVNTSRTE-PGRAKPAETGQKRKQEAERSEGM-----KERMK--------RGRLEMCE-K 58

  Fly    62 APCCRDIHGKEPPDGGARAWLVMVSAFL---CNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSK 123
            .||.     ...|||| ..|:::...||   |...:...::.:.|...|...|        ..|.
Zfish    59 NPCL-----ATAPDGG-WGWMIVAGCFLTTVCTRAVTRCVSIFFVEFQLYFSR--------DYSA 109

  Fly   124 AALIGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFG 188
            .|.|.:|...||.|.:.:...:.:::..|:....||:||:.||||||..| ::..||.|.|::.|
Zfish   110 TAWIHSLLDCTTMLCAPLGSYIGNRLSSRIAIMIGGLLSSTGLLLSSLAT-SVEFLYLTLGVLTG 173

  Fly   189 LGAALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSA 253
            :|.||:|||.:|::|.||::......|...:||.:.|.||.|.:..|:..:...|.|.|::.:.:
Zfish   174 VGFALSYTPAIAMVGSYFRQRKALAYGIAMSGSGIGTFILAPAVQLLIEFFSWRGALLILAGLVS 238

  Fly   254 FIILCSFVYKPLH----------------------------------------------PPPE-- 270
            .:..|..:.:||.                                              .|.|
Zfish   239 HLCFCGALMRPLQSQRGRQNKMDLENGKTVDLLNVKLAYVELRGSMEVTHAVVKEMEKKEPSENM 303

  Fly   271 ----------------------------------------------------------------- 270
                                                                             
Zfish   304 LRNGKGWIEADDMKQSHLDEEENHGQDLSENPKTVNKWSEEEPRTISIPALVQSSGLPLENLLKY 368

  Fly   271 ------PPKKKPGRSRINLFLRS-IINVEIWKRKRFVIWA------------LCVP--------- 307
                  |..|..|.:..:...:| ::..::.|..:..:|:            |.:|
Zfish   369 QKNITFPESKSEGNNNQSTVAKSKVVKAKLLKESKENVWSVLRKTVLKEYSFLLIPDFLLLLVSF 433

  Fly   308 -LALFGYFVPYVHMMQF-VKTTFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVN--RMYLQQL 368
             ...:|..||:|:::.: :......:...|.:..:|::..||.:.||.|||...:.  |:....|
Zfish   434 LFLAYGCSVPFVYLVPYSLSAGVSPQQAALVMSILGVSGIIGTITFGWIADRKCLRPYRVVSYML 498

  Fly   369 SLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSI 433
            ::.|.||..|.|||.:.:.:||.|:|:.|.|||.:::|:..:..:....:..|.|:|.:..|.:|
Zfish   499 AVGSEGLSCLFLPLLSGFSLLVPFSLIYGYFDGAYVALIPVVTSDTVSSAQLTSALGVVYFLHAI 563

  Fly   434 PLTVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCV 476
            |..:.||:.|.:.|.|.|||...||:|:..:..:.:|..:|.:
Zfish   564 PYLISPPIGGWLVDQTGSYTATFILSGVSLICSAVILAAVKVI 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	114/541 (21%)
slc16a12a	XP_009291327.2	None