Protein Alignment kar and slc16a3

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001007912.1
• Gene: slc16a3 / 493294
• XenbaseID: XB-GENE-483002
• Length: 473
• Species: Xenopus tropicalis
• Alignment Length: 439
• Identity: 121/439 - (27%)
• Similarity: 197/439 - (44%)
• Gaps: 58/439 - (13%)

  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGT 134
            |.:.|||| ..|.|:...|:..|..:.|.....|....|. |...:|..:.:..::::.|:..||
 Frog    12 GVKAPDGG-WGWAVLFGCFVITGFSYAFPKAVSVFFKELI-REFGIGYSDTAWISSILLAMLYGT 74

  Fly   135 TFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTL 199
            ..|.|.   |: ::.|.|.....||:.:|.|::.:|||| :|..:|.|.|::.|||.||.:.|:|
 Frog    75 GPLCSI---CV-NRFGCRPVMMVGGLFAALGMVAASFCT-SILTIYLTAGVITGLGLALNFQPSL 134

  Fly   200 AILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKP 264
            .:|..||.:.....:|...|||.||...|.|....|...:|..|...|:..:......|..:.:|
 Frog   135 IMLNRYFDKRRPLANGLAAAGSPVFLCALSPLGQILQYEFGWRGGFLILGGLLLNCCACGALMRP 199

  Fly   265 LHPPPE-----------PPKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYV 318
            |.||.:           .||||            :::..::|.:.|||:.|...:.:.|.|||.|
 Frog   200 LEPPKKAVEEVKDTKEIKPKKK------------LLDFSVFKDRGFVIYTLAASIMVLGLFVPPV 252

  Fly   319 HMMQFVKTTFPGEDVNLP-------VMCIGITSGIGRLIFGVIADMPGVN--RMYLQQLSLVSIG 374
            .::.:.|      |:.:|       :..:|......|...|||..:..|.  .:||...::|..|
 Frog   253 FVVSYAK------DIGIPDTKAAFLLTVLGFIDIFARPTCGVITGLKQVRPYAVYLFGFAMVFNG 311

  Fly   375 LVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYE----ICGPSGATQAIGFLLGLSSIPL 435
            ...|:..:.:|:..||.|.:..|:..|    ::|.:.:|    |.|....:.|||.:|...:..:
 Frog   312 FTDLMGSMADSFGGLVVFCIFFGISYG----MVGALQFEVLMAIVGTHKFSSAIGLVLLAEACAV 372

  Fly   436 TVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLL-----FLIKCVKEE 479
            .:|||.||.|.|:|..|....|:||:..:..:.:|     |.||...||
 Frog   373 LIGPPSAGKILDATGKYMFVFIIAGVEVVTSAFVLTLGNFFCIKKTVEE 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	112/422 (27%)
slc16a3	NP_001007912.1	MFS_MCT3_4	21..411	CDD:340988	111/417 (27%)