Protein Alignment kar and hrm

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Alignment Length: 660
• Identity: 145/660 - (21%)
• Similarity: 227/660 - (34%)
• Gaps: 218/660 - (33%)

  Fly    37 NGKDAMKPSAPVQNGNGNAN-GTHIEAPCCRDIHGKE----PPDGGARAWLVMVSAFLCNGIIFG 96
            |.::|.|.:......|||.| ..|...........||    ||||| ..|||::.:.|.|.:|.|
  Fly     8 NSQNASKINQKDHKPNGNTNESRHKTVSLINKKDDKEYDLVPPDGG-WGWLVLLGSCLTNILIPG 71

  Fly    97 FINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLFSTM---AGCLTDKIGLRLTTFAG 158
            .|.::||:.|..||...     .:.:|||.|.||..   ||:|::   :..|:.|...|..|..|
  Fly    72 TIKSFGVLFSEFTDAFN-----SSPTKAAWIPALCY---FLYSSLGPVSSILSVKYSYRTVTLLG 128

  Fly   159 GVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAILGHYFKRYLGKVSGFVTAGSSV 223
            |..::.|::| ||...:|..||.:||::.|:||.|::.||:.|:..||.:..|..:|...:||::
  Fly   129 GASASLGMIL-SFWASSIEFLYISYGVLVGIGAGLSFPPTVYIVTSYFAKLRGLANGLCISGSAL 192

  Fly   224 FTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLH---------------------- 266
            .::||||.|..||.:||..|:..||..::..:.:.:..|:|:.
  Fly   193 GSIILPPLLRWLLETYGYHGSCLIMGGITLNVFVAALFYEPVEQHMVRVPRARQALENIPEEEDI 257

  Fly   267 -------------PPPEPPKKK-------------PGRSRINLFLRSIINV----------EIWK 295
                         |..||..|.             ||..|:. |:||....          |...
  Fly   258 GIVMKFENVDEPVPKNEPADKPLLPYNSPPSPLYLPGDERLQ-FVRSASAAVVQSYSKSGDEFQS 321

  Fly   296 RKRFVIWALCVP-----------------------------LAL-------FGYFVPYVHMMQFV 324
            |.|.:...:.:|                             |.|       .....|......:|
  Fly   322 RSRKISTPVRLPQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTLRNSSKSRLSKRSPSTSSFLYV 386

  Fly   325 KTTFPGE-------------------------------------DVN------------------ 334
            .|.:.|.                                     ||:
  Fly   387 STPYHGSTLSFQPKEFSSHLSLRSMGSSGTGHAGDSTGQDGSYADVDARGQAQQPQRSKFFDLSL 451

  Fly   335 --------------------------LP----------------VMCIGITSGIGRLIFGVIADM 357
                                      ||                :..:..|..|||:....::||
  Fly   452 LKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFNKSLSAYLLSVVSATDLIGRIGGSALSDM 516

  Fly   358 PGVNRMYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQ 422
            ..:.:.:.....|...||...|||...:|..:..:..:.||..|.::.:...|..::.|....|.
  Fly   517 GYIPKTWYFVGGLSISGLSLALLPFAWTYSSVCFWCALFGLASGIYVGITAVIMADMLGTERLTS 581

  Fly   423 AIGFLLGLSSIPLTVGPPVAGMIFDSTNSYTLPLILA-GLPPLLGSSLLFLI------KCVKEEE 480
            :.|..|.::.:...||||:....|::.|.|. ||..| ||..|.|:||...:      |...||:
  Fly   582 SYGISLFVNGLLQLVGPPLCNYWFEAVNDYN-PLFHALGLTLLAGASLWSFMPWINRRKANAEEQ 645

  Fly   481 NGVSAPRAVV 490
            ......:|.|
  Fly   646 LDAQIEKAAV 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	125/594 (21%)
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	62/184 (34%)
		MFS	<451..633	CDD:475125	39/182 (21%)