DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kar and CG14196

DIOPT Version :9

Sequence 1:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_573367.1	Gene:	CG14196 / 32915	FlyBaseID:	FBgn0031002	Length:	600	Species:	Drosophila melanogaster

Alignment Length:	230	Identity:	59/230 - (25%)
Similarity:	104/230 - (45%)	Gaps:	37/230 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 PDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLF 138
            ||.| .||:|.|:|.:.|..|:..:..:|.   |..:||:.||  .:||:...|    |......
  Fly    37 PDAG-WAWIVCVAAGVSNLSIYPCLQQFGF---LFRERLSDLG--MSSSQITAI----INANPAV 91

  Fly   139 STMAGCLTDKIGLRLT----TFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTL 199
            |...|.|...:..|.|    ..||.:|.:|.|:|::|| |...:....|.::||.|..::.:.:.
  Fly    92 SACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFC-ETFLSYMVAYALLFGFGMGISVSASS 155

  Fly   200 AILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKP 264
            ..:..||::...:.:||....:.:..:.||..:..||..||::||..:.:.:|....:|:.:|:|
  Fly   156 LAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQP 220

  Fly   265 LHPPPEPP----------------------KKKPG 277
            :....:||                      |::||
  Fly   221 VRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPG 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	55/223 (25%)
kar	NP_001189213.1	MFS_1	124..439	CDD:284993	41/180 (23%)
CG14196	NP_573367.1	MFS	71..>221	CDD:119392	40/156 (26%)
CG14196	NP_573367.1	MFS	<410..579	CDD:119392
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.891027	Normalized mean entropy	S3509
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870