Protein Alignment kar and Slc16a4

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001013935.1
• Gene: Slc16a4 / 295356
• RGDID: 1359655
• Length: 500
• Species: Rattus norvegicus
• Alignment Length: 479
• Identity: 109/479 - (22%)
• Similarity: 197/479 - (41%)
• Gaps: 87/479 - (18%)

  Fly    72 EPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            :|.||| ..|:|::..||.|..:.|...|:.:...:..:..     ...|.:...||::.....|
  Rat    13 KPLDGG-WGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEF-----EGTSEQIGWIGSIMSSLRF 71

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            ....:|..:.|..|.:.|:..|..|.:||.|:||:.| .|..|..|.|::.|||:|..|.....:
  Rat    72 SAGPLAAIICDIFGEKTTSILGTFLVSGGYLISSWAT-GIPFLCVTMGLLPGLGSAFLYQVAAVV 135

  Fly   202 LGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLH 266
            :..|||:.||..:....:|..: |.:|.|....|:..|...|.|.:...::..::..|.:.:|:|
  Rat   136 ITKYFKKRLGLSTAIARSGMGL-TFLLAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVH 199

  Fly   267 ------------------PPPE-------PPKKK------------------------------- 275
                              ..||       |.:.|
  Rat   200 IQSDSNSDIKNKGSILSATGPELSHKTETPNRNKAQESLIKDSAVKKSGQPTTTLTVLENQIEEI 264

  Fly   276 ---PGRSRINLF---------------LRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQ 322
               |.|:|..|.               ...::::.:::...|.|:.....|:...||:|..|::.
  Rat   265 STRPHRNRPLLMSNDKTYKKKFVSWNCKEKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVA 329

  Fly   323 FVKTTFPGEDV---NLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVTLLLPLTN 384
            ..||.  |.|:   :..|...|||..:.:||.|.|||...:.:....:..|:..|:..||.||..
  Rat   330 RAKTL--GIDIMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGVTNLLAPLAT 392

  Fly   385 SYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDST 449
            ::.:|:::|:...:|.|.:::|:.|:..::...|...:.:|:....:.:.:..|||:||.|:|.|
  Rat   393 TFPLLMAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRFLGYASFFAGMAVLSGPPIAGWIYDYT 457

  Fly   450 NSYTLPLILAGLPPLLGSSLLFLI 473
            .:|......:|...:|.|..||.:
  Rat   458 QTYVGSFYFSGTCYILSSVSLFFV 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	105/471 (22%)
Slc16a4	NP_001013935.1	MFS_MCT5	20..486	CDD:340979	105/471 (22%)