back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment kar and Slc16a2

DIOPT Version :10

Sequence 1:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_671749.2	Gene:	Slc16a2 / 259248	RGDID:	628608	Length:	545	Species:	Rattus norvegicus

Alignment Length:	423	Identity:	164/423 - (38%)
Similarity:	266/423 - (62%)	Gaps:	16/423 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGT 134
            |.:||:||. .|:|:.:|..|||.|||..|:.|:::|:|.:. .|..:.:...:||.:||||:|.
  Rat    97 GFQPPEGGF-GWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGM 159

  Fly   135 TFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTL 199
            .|..|.:....||::|.|:|...|..::..||..||| |.::...||||||:||.|.:.|:.|:|
  Rat   160 IFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSF-TSSLSLRYFTYGILFGCGCSFAFQPSL 223

  Fly   200 AILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGS-YGLEGTLRIMSLVSAFIILCSFVYK 263
            .||||||:|.||..:|.|:||||:|::.. |.|.|:||. ..|..|.:::|.....:.|.|..|:
  Rat   224 VILGHYFQRRLGLANGVVSAGSSIFSMSF-PFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYR 287

  Fly   264 PLHPPPEPPKKKPG----RSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFV 324
            ||.|..:....|.|    |.|..:..|...|:.:::::.:.|||..:..|..||||||||:|::|
  Rat   288 PLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYV 352

  Fly   325 KTTFPG-EDVNLPVMCIGITSGIGRLIFGVIAD-MPGVNRMYLQQLSLVSIGLVTLLLPLTNSYV 387
            :..|.. ::..:.::|||.|||:|||:.|.|:| :||:.::|||.||.:.:||:::::||...:.
  Rat   353 EDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFG 417

  Fly   388 ILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSY 452
            .|:...|.:||.||.||:::.|||:|:.||..|:||||:|||:.::|:..|||:||::.:...:|
  Rat   418 GLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNY 482

  Fly   453 TLPLILAGLPPLLGSSLLFLI-----KCVKEEE 480
            .:....||:||::|:.:||.:     :..|:|:
  Rat   483 HVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQ 515

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.