Protein Alignment kar and SLC16A9

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_016871372.1
• Gene: SLC16A9 / 220963
• HGNCID: 23520
• Length: 551
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 133/527 - (25%)
• Similarity: 207/527 - (39%)
• Gaps: 133/527 - (25%)

  Fly    71 KEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTT 135
            |:.|||| ..|:::..:||...:.:|.....||::   .:.|...|  |...|.|.:|:||.|..
Human     4 KKSPDGG-WGWVIVFVSFLTQFLCYGSPLAVGVLY---IEWLDAFG--EGKGKTAWVGSLASGVG 62

  Fly   136 FLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLA 200
            .|.|.:........|.|..|...|.:.||||:|||| ..||..|:|:|||:.|||..|.||.|:.
Human    63 LLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSF-APNIYFLFFSYGIVVGLGCGLLYTATVT 126

  Fly   201 ILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPL 265
            |...||....|...|.::.||||...|.......|:..|||:|.|.|:..::..|:.|..:.:||
Human   127 ITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPL 191

  Fly   266 HPPPEP-PKK--------------KPGRS---RINLFLRSIINVE---------IWKR------- 296
            .....| |||              :.|::   .||:..:|..:.|         .||:
Human   192 QSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGDWKQDSLLHKN 256

  Fly   297 ---------------------------------------------KRFVIWALCVPLALF--GYF 314
                                                         |..|..||.:.:.||  |.|
Human   257 PTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVFSALFIAILLFDIGGF 321

  Fly   315 VPYVHMMQFVKTT-FPGEDVNLP-VMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVT 377
            .|.:.|....::: ...|:..:| :..|||.:.:|:|:.|::||...:|.:||...:|:.:||..
Human   322 PPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLAL 386

  Fly   378 LLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVA 442
            ..:|...|||.|...:.::|...|.: |:...:..:..|......|.|.|:..:.:..::|||:.
Human   387 CAIPFAKSYVTLALLSGILGFLTGNW-SIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIV 450

  Fly   443 GMIF------------------------------------------DSTNSYTLPLILAGLPPLL 465
            |.||                                          |.|.:|.:....:|...||
Human   451 GKIFILKSSHFTVLPCHISRYRGPDCNSSTDLYKRNLHGTSHGWFYDWTQTYDIAFYFSGFCVLL 515

  Fly   466 GSSLLFL 472
            |..:|.|
Human   516 GGFILLL 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	128/518 (25%)
SLC16A9	XP_016871372.1	MFS_MCT9	12..524	CDD:340986	128/518 (25%)