Protein Alignment kar and Slc16a11

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_694721.2
• Gene: Slc16a11 / 216867
• MGIID: 2663709
• Length: 447
• Species: Mus musculus
• Alignment Length: 457
• Identity: 120/457 - (26%)
• Similarity: 200/457 - (43%)
• Gaps: 45/457 - (9%)

  Fly    73 PPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFL 137
            ||||| ..|:|..:||..||:.:|.:.:.|:....|.:...:     ::...|.:.|||:.....
Mouse     8 PPDGG-WGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFER-----SAQDTAWVSALALAVQQA 66

  Fly   138 FSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAIL 202
            .|.:...|:.:.|.|.....||||::.||:.|:| ..::..||...|::.|.|.||.:.|.|..|
Mouse    67 ASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAF-ARSLLHLYLGLGLLAGSGWALVFAPALGTL 130

  Fly   203 GHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLHP 267
            ..||.|......|....|:...:::|.|.|..||.::|..|.|.::..|:..:..|..:.:||..
Mouse   131 SRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLAL 195

  Fly   268 PPEP--PKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHM-MQFVKTTFP 329
            ..:|  |.:.|         .:.:.:.::||:.|.::||...|...||||||||: ...:.....
Mouse   196 SGDPLAPPRTP---------LAALGLGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMG 251

  Fly   330 GEDVNLPVMCIGITSGIGRLIFGVIADMPGV--NRMYLQQLSLVSIGLVTL-LLPLTNSY----V 387
            |....|.|....:.....||..|.:||...|  .|:.:...||..:|::.: |:|...:.    .
Mouse   252 GYGAALVVAVAAVGDACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGA 316

  Fly   388 ILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSY 452
            .|::.....||..|.:..|:..:...:.|..|..||.|.::.|.|:...:|||::|.:.|.|..:
Mouse   317 PLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDF 381

  Fly   453 TLPLILA------------GLPPLLGSSLLFLIKCVKEEENG--VSAPRAVVLANGDIEIAGNGH 503
            :...::.            |||..|.|............|.|  :..|:..:|:.|     |.|.
Mouse   382 SASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSAG-----GTGS 441

  Fly   504 YR 505
            .|
Mouse   442 IR 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	107/415 (26%)
Slc16a11	NP_694721.2	MFS	14..403	CDD:475125	103/403 (26%)