Protein Alignment kar and Slc16a1

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_033222.1
• Gene: Slc16a1 / 20501
• MGIID: 106013
• Length: 493
• Species: Mus musculus
• Alignment Length: 454
• Identity: 110/454 - (24%)
• Similarity: 186/454 - (40%)
• Gaps: 57/454 - (12%)

  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFG-------FINTYGVIHSLLTDRLTKLGDPEASSKAALI 127
            |..||||| ..|.|:|.||:..|..:.       |.....||.|..|            |:.:.|
Mouse    10 GYTPPDGG-WGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATT------------SEVSWI 61

  Fly   128 GALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAA 192
            .::.:...:....::..|.:|.|.|....|||.||..||:.:||| ..:..||...|::.|||.|
Mouse    62 SSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFC-NTVQELYLCIGVIGGLGLA 125

  Fly   193 LAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIIL 257
            ....|.|.::|.||.:.....:|...|||.||...|.|........:...|:..|:..:.....:
Mouse   126 FNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCV 190

  Fly   258 CSFVYKPLHPPP---EPPKKK-------------------PGRSRINLF--LRSIINVEIWKRKR 298
            ...:.:|:.|..   |..|.|                   |...::::|  :...:::.::..:.
Mouse   191 AGSLMRPIGPEQVKLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRG 255

  Fly   299 FVIWALCVPLALFGYFVPYVHMMQFVKT-TFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNR 362
            |:::.....:..||.|.|.|.:..:.|: .|..|.....:..:.....:.|...|:.|:...:..
Mouse   256 FLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRP 320

  Fly   363 --MYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIG 425
              .|....|:|:.|:..||.||:.:||....:..|.|...|...|:|.....::.||...:.|:|
Mouse   321 RIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVG 385

  Fly   426 FLLGLSSIPLTVGPPVAGMIFDSTNSYT-------LPLILAGLPPLLGSSLLF--LIKCVKEEE 480
            .:..:...|:.:|||:.|.:.|....|.       :.||:||:...:|..:.:  |.|..|.||
Mouse   386 LVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	100/436 (23%)
Slc16a1	NP_033222.1	2A0113	1..466	CDD:273325	110/454 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	447..493		2/3 (67%)