DRSC/TRiP Functional Genomics Resources

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Protein Alignment kar and Slc16a1

DIOPT Version :9

Sequence 1:NP_001189213.1 Gene:kar / 45883 FlyBaseID:FBgn0001296 Length:612 Species:Drosophila melanogaster
Sequence 2:NP_033222.1 Gene:Slc16a1 / 20501 MGIID:106013 Length:493 Species:Mus musculus


Alignment Length:454 Identity:110/454 - (24%)
Similarity:186/454 - (40%) Gaps:57/454 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFG-------FINTYGVIHSLLTDRLTKLGDPEASSKAALI 127
            |..||||| ..|.|:|.||:..|..:.       |.....||.|..|            |:.:.|
Mouse    10 GYTPPDGG-WGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATT------------SEVSWI 61

  Fly   128 GALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAA 192
            .::.:...:....::..|.:|.|.|....|||.||..||:.:||| ..:..||...|::.|||.|
Mouse    62 SSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFC-NTVQELYLCIGVIGGLGLA 125

  Fly   193 LAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIIL 257
            ....|.|.::|.||.:.....:|...|||.||...|.|........:...|:..|:..:.....:
Mouse   126 FNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCV 190

  Fly   258 CSFVYKPLHPPP---EPPKKK-------------------PGRSRINLF--LRSIINVEIWKRKR 298
            ...:.:|:.|..   |..|.|                   |...::::|  :...:::.::..:.
Mouse   191 AGSLMRPIGPEQVKLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRG 255

  Fly   299 FVIWALCVPLALFGYFVPYVHMMQFVKT-TFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNR 362
            |:::.....:..||.|.|.|.:..:.|: .|..|.....:..:.....:.|...|:.|:...:..
Mouse   256 FLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRP 320

  Fly   363 --MYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIG 425
              .|....|:|:.|:..||.||:.:||....:..|.|...|...|:|.....::.||...:.|:|
Mouse   321 RIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVG 385

  Fly   426 FLLGLSSIPLTVGPPVAGMIFDSTNSYT-------LPLILAGLPPLLGSSLLF--LIKCVKEEE 480
            .:..:...|:.:|||:.|.:.|....|.       :.||:||:...:|..:.:  |.|..|.||
Mouse   386 LVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEE 449

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
karNP_001189213.1 MFS 81..459 CDD:119392 96/418 (23%)
MFS_1 124..439 CDD:284993 76/341 (22%)
Slc16a1NP_033222.1 2A0113 1..466 CDD:273325 110/454 (24%)
MFS 20..432 CDD:119392 98/424 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 447..493 2/3 (67%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2504
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D916876at2759
OrthoFinder 1 1.000 - - FOG0000033
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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