Protein Alignment kar and SLC16A13

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_963860.1
• Gene: SLC16A13 / 201232
• HGNCID: 31037
• Length: 426
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 120/443 - (27%)
• Similarity: 209/443 - (47%)
• Gaps: 48/443 - (10%)

  Fly    72 EPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            |||||| ..|:|::|||..:.::||.:.::||.........     .|.:::.:.|.::.|....
Human     6 EPPDGG-WGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAF-----EEQAARVSWIASIGIAVQQ 64

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            ..|.:...|:.|.|.|.....||:|:|.|:||:||.| ::..||.:.|::.|.|.||.:.||||.
Human    65 FGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFAT-SLTHLYLSIGLLSGSGWALTFAPTLAC 128

  Fly   202 LGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLH 266
            |..||.|.....:|....|..:.:....|....||..|...|:|.::|.:|..::.|..:.:|..
Human   129 LSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPS 193

  Fly   267 PPPEPPKKKPGRSRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTTFPGE 331
            ...:|....| |:::...|.         ...|:.:.:.:.|...|||:||:|::..:      :
Human   194 LAEDPAVGGP-RAQLTSLLH---------HGPFLRYTVALTLINTGYFIPYLHLVAHL------Q 242

  Fly   332 DVN---LP----VMCIGITSGIGRLIFGVIAD-MPG-VNRMYLQQLSLVSIGLVTLLLPLTNSYV 387
            |::   ||    :..:.|:..:||::.|.:.| :|| |.|:.:...:|..:.|.  |.|:..:..
Human   243 DLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLA--LFPVAQAPT 305

  Fly   388 ILVSFTLVMGLFDGCFISLLGPIAY----EICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDS 448
            .||:..:..|...|.    |.|:|:    |:.|.......:|.|..:.||...:|||::|.:.|.
Human   306 ALVALAVAYGFTSGA----LAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDV 366

  Fly   449 TNSYTLPLILAGLPPLLGSSLLFLIK---CVKEEENGVSAPRAVVLANGDIEI 498
            |.:||...::||...|.||.:|..:.   |.....:|   |:.:|....|.::
Human   367 TGNYTASFVVAGAFLLSGSGILLTLPHFFCFSTTTSG---PQDLVTEALDTKV 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	103/390 (26%)
		MFS_1	124..439	CDD:284993	85/327 (26%)
SLC16A13	NP_963860.1	MFS	14..392	CDD:119392	109/405 (27%)
		MFS_1	21..357	CDD:284993	91/363 (25%)
		DUF3172	369..>419	CDD:288260	13/51 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100246
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.720