Protein Alignment kar and mct-1

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_503655.2
• Gene: mct-1 / 189489
• WormBaseID: WBGene00021227
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 484
• Identity: 116/484 - (23%)
• Similarity: 195/484 - (40%)
• Gaps: 111/484 - (22%)

  Fly    73 PPDGGARAWLVMVSAFLCNGIIFGFINTYG-VIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            ||||| ..|:|:.::||.|..:.|.|.|.| ::..:..|:.      .::|.|..:.::..|..:
 Worm    39 PPDGG-YGWVVVAASFLVNMAVDGVIYTCGKILVPIWADQF------GSTSVAGAVISILTGCYY 96

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            |...:|....:..|:|....||.:|:....|||.|.: .|..||..:|::.|:|....|.|::.|
 Worm    97 LAGPLASSFVNVFGIRSVAIAGSILATTAFLLSRFAS-TIWELYLLFGVLGGIGFGCMYLPSIVI 160

  Fly   202 LGHYFKRYLGKVSGFVTAGSS----VFTVILPPCLD---KLLGSYGLEGTLRIMSLVSAFII--- 256
            |..||.:.....:|....||.    ||:.|..|..|   |.:||:        |..::|..|
 Worm   161 LSTYFAKKRSVATGIAVCGSGIGTMVFSTINGPVFDYFGKDVGSF--------MVYLAAIAISGS 217

  Fly   257 LCSFVYKPLH------------------PPPEPPKK-------------KPG------------- 277
            |.|.::.||.                  .|.||.::             :||
 Worm   218 LFSLLFAPLKATEHQVKKVAKMVRNYEGKPEEPTQRLLEDVRNDLEELNRPGHNADTFYAGNAPV 282

  Fly   278 -RSRINLFLRS--------IINV-------EIWKRKRFVIW--ALC-------------VPLALF 311
             |||.|...|.        :::.       .:.|:.:|..:  :||             :.||:.
 Worm   283 SRSRSNTLDRKAAESAEAHVVHATEHHTVHHVVKKSKFTKFKESLCSVLDKDLLFSPSFMTLAVS 347

  Fly   312 GYF------VPYVHM---MQFVKTTFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQ 367
            |.|      ||:|::   |:.....|...:::|||..||..:.:.|:..|::||.|.::.:.:..
 Worm   348 GTFTVLSFLVPFVYLALAMKQKNPDFTDAELSLPVTLIGAFNIMFRIGCGMVADHPKMSALQVSN 412

  Fly   368 LSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSS 432
            ::.:..|...|.:|........|.|.:.......||.:|...|..|:.|....:.|.|.|:....
 Worm   413 VATIIAGTSMLFVPFCTELWHYVVFCIPFSAGVACFAALRSVICVELIGVEKLSNAFGILMVFMG 477

  Fly   433 IPLTVGPPVAGMIFDSTNSYTLPLILAGL 461
            |...||.|:|..|.|.|.:|.:...:.|:
 Worm   478 IGAVVGGPIAAQIKDITGNYDISFYVMGI 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	110/472 (23%)
		MFS_1	124..439	CDD:284993	92/408 (23%)
mct-1	NP_503655.2	MFS_MCT_SLC16	45..519	CDD:340910	111/477 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4103
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H75089
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100246
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720