Protein Alignment kar and mct-5

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_495464.2
• Gene: mct-5 / 187995
• WormBaseID: WBGene00020168
• Length: 591
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 114/574 - (19%)
• Similarity: 199/574 - (34%)
• Gaps: 172/574 - (29%)

  Fly    73 PPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFL 137
            ||||| ..|:|::.:|..:....||:.::|::...|.....     ..::..:||.::..|.|..
 Worm    14 PPDGG-WGWVVVIGSFFIHVFADGFVYSFGILAEKLMIEFN-----SNNTMTSLIVSMLTGFTLG 72

  Fly   138 FSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAIL 202
            ...:|..:.:|.|.|:||..|..::..|.|||.|.|| |.....:.|::.|:|..|.|.|.:.|:
 Worm    73 AGPLASAVCNKYGCRITTIIGAGVAFVGCLLSCFATE-IWHFVISVGVIMGIGFGLVYCPAIVIV 136

  Fly   203 GHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLH- 266
            ..||:......:|...||:.|..|:..|....::.:||......:...|.....:|...:.||.
 Worm   137 TMYFESKRSLATGIAVAGAGVGAVVFGPINTFIISNYGWRYVFVLFLFVIILCAVCGATFVPLQF 201

  Fly   267 ------------------------------------PPPE-------------------PPKKKP 276
                                                .||:                   .|....
 Worm   202 ALVPDDDDDGEYNDVFEDEVKKIDYNKRFEEKVSLLSPPQVLERSMSQCCDIQKNNQHARPSSSV 266

  Fly   277 GRSRINLFLR-----------------------SIINVEIWKRK--------------------- 297
            |...:...||                       ||.||..::..
 Worm   267 GAVDLEPLLRPRCGTIGERNSGYLNRKDVFYTGSISNVAEFRANPDKYRSTGSLHTALNIHTHHT 331

  Fly   298 -----------------------------------------------------RFVIWALCVPLA 309
                                                                 .|:::|:...|.
 Worm   332 GTVGDDRESGHGCDQSLDGMNEKKETDFMDDIEGSNMFKTINNMFSFQLLLDPAFLLFAISNLLT 396

  Fly   310 LFGYFVPYVHMMQFVKTTFPGEDVNLPVMCI-GITSGIGRLIFGVIAD----MP-GV------NR 362
            ..|:..|...:...|.......:|:..::.: |..:.||||||||:||    :| |:      ||
 Worm   397 SVGFNSPLYFLPLHVTNILSDNNVSGNILSVYGTANTIGRLIFGVVADQKLPLPAGLGDDTARNR 461

  Fly   363 MYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFL 427
            :::..:||...|:||......:.|::|..:.::.|.....::.|...|..::.|....|.|.|.|
 Worm   462 LWMYNISLTICGIVTAFCYKFDGYILLDIYAVLFGFTIASYVCLTSVILVDLLGLDKLTNAFGLL 526

  Fly   428 LGLSSIPLTVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEEN 481
            |....:...:||.|:|.:.|.|.:|||..:..|:..::...:||:|...|.:::
 Worm   527 LLWQGVGTVIGPLVSGYLADLTGNYTLSFVFCGINLMVSGLMLFVIPYFKRKDD 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	104/542 (19%)
		MFS_1	124..439	CDD:284993	88/479 (18%)
mct-5	NP_495464.2	MFS_MCT_SLC16	20..573	CDD:340910	107/558 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820