Protein Alignment kar and mct-3

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_510308.1
• Gene: mct-3 / 181497
• WormBaseID: WBGene00010834
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 121/568 - (21%)
• Similarity: 207/568 - (36%)
• Gaps: 164/568 - (28%)

  Fly    73 PPDGGARAWLVMVSAFLCNGIIFGFINTYGVI------HSLLTDRLTKLGDPEASSKAALIGALA 131
            ||||| ..|.::.::||.|.|:.|.|.|.|.|      ||        .|..|||  ||:..::.
 Worm    33 PPDGG-YGWAIVAASFLLNMIVDGVIFTVGKILQPAWVHS--------FGISEAS--AAMTMSIL 86

  Fly   132 IGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYT 196
            .|..|....:|..|.:..|.|....||.:::|.|.|| |....||..||.::|::.|.|..:.|.
 Worm    87 SGCYFFAGPIASVLCNVFGCRQVALAGSLIAALGFLL-SISAPNIYVLYVSFGLIAGAGFGMMYL 150

  Fly   197 PTLAILGHYFKRYLGKVSGFVTAGSSVFTVI---------------------------------- 227
            |.:.|:..||.:.....:|....||.:.|.:
 Worm   151 PAIVIISQYFAKKRSVATGIAVCGSGIGTTVFALLNDVVWDFVGGDWKQFLVYTAAVTISGLGAC 215

  Fly   228 -----LPPCLD------KLLGSY----------------------GLE----GTLR-------IM 248
                 |.|..|      |:|..|                      .||    |.|.       |.
 Worm   216 ILLRPLKPSKDQIEKVAKVLEDYEEHKEKVPESPLLSKHNTPFLSSLELHTAGKLENGHHTGSIK 280

  Fly   249 SLVSAFIILCSFVYKPL------------------------------HPPP-------EPPKKKP 276
            |:|.|.......:.|||                              |...       |.|::..
 Worm   281 SIVDAVSKEIEDLNKPLLRKDIFYSGSTTNIAARSRTGTMTREEAAEHQQSLRFRGKVETPQQYL 345

  Fly   277 GRSRINL-------------------FLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQ 322
            .::.:|.                   .|:.:::.|:.....|::.|....|.|..::||::::..
 Worm   346 SKADLNAGDNGDVAIANESKIQEIKQALKQLVDKELLFSPSFLLLAFSGTLTLCCFYVPFIYLGN 410

  Fly   323 FVK-----TTFPGEDVNLPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVTLLLPL 382
            .:.     ||   .:.:..|..||:.:.:.|:..|::||.|.|:.:.:...:|::.||.|:.:||
 Worm   411 HLDKIEGLTT---AEKSFTVSLIGVLNIVARIGCGILADRPEVSALAVNNFALIAAGLATMTVPL 472

  Fly   383 TNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFD 447
            ..:|...::|.:...:...||.:|...|..|:.|....:.|.|.||....:...||.|:|..:.|
 Worm   473 YTAYWQFLAFCVPFSIGVACFAALRSIIVVELIGLEKLSNAFGILLTFMGVGAVVGSPLAAAMKD 537

  Fly   448 STNSYTLPLILAGLPPLLGSSLLFLIKCVKEEE----NGVSAPRAVVL 491
            .|.::.....:.|....:..::...:..:::.|    :...|.:|:.|
 Worm   538 YTGNFDTSFYVMGALMTISGAMCIPLGGLRKRELARSDSSDAKKAIEL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	111/522 (21%)
		MFS_1	124..439	CDD:284993	90/453 (20%)
mct-3	NP_510308.1	MFS_MCT_SLC16	39..563	CDD:340910	112/537 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	1.000	Domainoid score	I4103
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H75089
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820