Protein Alignment kar and mct-4

DIOPT Version :9

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: NP_001041267.1
• Gene: mct-4 / 180766
• WormBaseID: WBGene00003986
• Length: 777
• Species: Caenorhabditis elegans
• Alignment Length: 655
• Identity: 119/655 - (18%)
• Similarity: 210/655 - (32%)
• Gaps: 257/655 - (39%)

  Fly    72 EPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            :.|||| ..|:::.:||:.|.::.|....:........:|.     .|:......||:|.|||..
 Worm    68 QAPDGG-YGWVIVFAAFMSNLVVDGISTAFSEFKQSYKERY-----QESDGLTVFIGSLIIGTYL 126

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            |...:...|.:|...|....|||::|....:::. .:.||......||:|.|||..:.|.|.:.:
 Worm   127 LVGPLVSALCNKYEQRYVVMAGGLISGIAFMIAP-ASPNIYVFMLIYGVMGGLGFGMIYLPAIVV 190

  Fly   202 LGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPL- 265
            :|.||.......:|...|||.|.|.::|......:.:.|.:.|:.:::::....:...::|:||
 Worm   191 VGFYFDSKRAMATGISVAGSGVGTFLVPLICQVCIANLGWQKTIWVLAVMIFSCVFYGYLYRPLP 255

  Fly   266 ---------------------------------HP------------------------------ 267
                                             ||
 Worm   256 MVDLNEIRDQEMEPLRQALSKVEDDEDEAVESPHPNRSTSAASGAIEDEAVSQNPEVQRLRSILT 320

  Fly   268 ----PPEPPK------------------------------------------------------- 273
                ..|.||
 Worm   321 EGDEGSETPKSDAHKVRSHTATRSRKHTMTSNSGSQHDLKLSRGNLSSDNRLSRVSARDFNQSLS 385

  Fly   274 --------------------------------------------KKPGR---------------- 278
                                                        |:.|.
 Worm   386 KLSKSGGASNLSIAMSGVDPKEFQRPMNRQDIFYGGSIQNLKEFKEEGTMAGYRASTLSIPRSVV 450

  Fly   279 ----SRINL--------------------------------------FLRSIINVEIWKRKRFVI 301
                |::||                                      .|..:|::.:.|.|..:|
 Worm   451 GQAVSQLNLSRTGSRLGGPGIAEDEEEMIEPFVDDGCCKVLPLPMRNALSEMIDLNLLKNKTMMI 515

  Fly   302 WALCVP--LALFGYFVPYVHMMQFVKTTFPGE--DVNLPVMCI---GITSGIGRLIFGVIADMPG 359
              ||:.  |.:.|:::|    :.|:|......  |::|.:..:   |:.:.|||:.||.:.|...
 Worm   516 --LCISNLLGMMGFYIP----IMFLKDLSESMKLDMSLAMFLVPIFGVFNTIGRVFFGWLTDQKI 574

  Fly   360 VNRMYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAI 424
            ::.:.:..|||:..||:||..||..|......:.:|.|.....:|.|...:..::.|....|.:.
 Worm   575 LSALTINNLSLIVSGLLTLACPLLTSIAGQYFYAIVFGFIISAYICLTSIVLADLMGLENLTNSF 639

  Fly   425 GFLLGLSSIPLTVGPPVAGMIFDSTNSYT-------LPLILAGLPPLLGSSLLFLIKCVKEEENG 482
            |.|:....|...||||.||:::|.|.||.       |.|::||   |:.:::.|:.|  |:.:..
 Worm   640 GLLVVARGIASLVGPPFAGIVYDITGSYDTAFYFGGLVLLVAG---LISATIPFVTK--KDADTA 699

  Fly   483 VSAPR 487
            ...|:
 Worm   700 DGMPQ 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	108/616 (18%)
		MFS_1	124..439	CDD:284993	90/546 (16%)
mct-4	NP_001041267.1	MFS_MCT_SLC16	75..>252	CDD:340910	43/182 (24%)
		MFS_MCT_SLC16	<507..689	CDD:340910	53/190 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920