Protein Alignment kar and LOC1273879

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_312909.4
• Gene: LOC1273879 / 1273879
• VectorBaseID: AGAMI1_011562
• Length: 687
• Species: Anopheles gambiae
• Alignment Length: 694
• Identity: 129/694 - (18%)
• Similarity: 219/694 - (31%)
• Gaps: 253/694 - (36%)

  Fly    21 AANGHTASATNGLVHANGKDAMKPSAPVQNGNGNANGTHIEAPCCRDIHGKEPPDGGARAWLVMV 85
            |.||.|     |.:.|||           ||||:......:.|....|   .||||| ..|||||
Mosquito    15 AENGAT-----GKLLANG-----------NGNGDTEKAKEDPPTTTLI---VPPDGG-WGWLVMV 59

  Fly    86 SAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFLFSTMAGCLTDKIG 150
            ::|.||.|:.|.:...|   |.|.....:.|..||  :.||:.:|..|...|.......|.::.|
Mosquito    60 ASFFCNVIVDGIVMNVG---SFLGPIRDEFGVSEA--EVALVSSLLSGFYLLTGPFVSALANRWG 119

  Fly   151 LRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAILGHYFKRYLGKVSG 215
            .|:.|..|.|::|.|..:|.:.| :|..||.|:|.:.|:|....|.|::..:|:||:::....:|
Mosquito   120 FRIVTIIGSVVAAVGFFVSQYAT-SIVFLYVTFGFIGGVGFCFIYVPSVITVGYYFEKWRAVATG 183

  Fly   216 FVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLHP------------- 267
            ....||.|.|.|..|....|:.|.|....|...:.:....|.|..:::|:.|
Mosquito   184 IALCGSGVGTFIFSPVNAMLIESLGWRSALVAQAAIILLCIACGAIFRPIQPTEVTATKAADTPA 248

  Fly   268 ----------------------------------------------------------------- 267
                                                                             
Mosquito   249 DKGILLGEGLPVVYTRPLPEGRYAYSMPNSSHNTWMGANPNYQYPTAAEIFRQGSGHNLDRRPSH 313

  Fly   268 ----------------------------------------------------------------- 267
                                                                             
Mosquito   314 TSGQLVSHNLQSTTKKLEKIQKRLAGQMTPDDTIHAHGYPTAHHELNPVGEADEEETENGTLLAA 378

  Fly   268 ----------------------PPEPPKKKPGRSR------------------------------ 280
                                  |.||...:.|..|
Mosquito   379 PEQQSVTITTAAGRRHTVSGRRPNEPASSRHGSRRTLNDGARPMYRDDIFFTGSLARIPQYKSQT 443

  Fly   281 -------------------------------INLFLRSIINVEIWKRKRFVIWALCVPLALFGYF 314
                                           :...|.:::::.:.|...|::.|....|.:.|:|
Mosquito   444 SLGYHMSVTRLPTQADVEETETEQCMVCPEAVRRTLVTMLDMSLLKSISFMMLAFSGFLTMMGFF 508

  Fly   315 VPYVHMMQFVKTTFPGEDVN-LPVMCIGITSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVTL 378
            ||::::.|........::|: ..|..|||::.|.|::.||:.....:|.::|..:::...|:.|:
Mosquito   509 VPFLYVKQRAVAGGMADEVSTFIVSAIGISNTIARVVCGVLTSFKNINALHLNNVAITLGGIATM 573

  Fly   379 LLPLTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAG 443
            :..:..:.|...::..:.||...||.:|...:..::.|....|.|.|.|.....|...:|.|:||
Mosquito   574 MSGMYITEVYQFTYAAIFGLAIACFSALRSILVVDLMGLEKLTNAFGILCLFQGIAAFLGAPIAG 638

  Fly   444 MIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEENGVSAPR 487
            ...:.|.:|.....::|....|.:.|.:.:..|...|...:|.:
Mosquito   639 YFTELTGTYDASFYISGALITLSAVLCYPLAFVNRWEKQRAAKK 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	107/620 (17%)
LOC1273879	XP_312909.4	MFS_MCT_SLC16	54..>231	CDD:340910	56/182 (31%)
		MFS	<479..668	CDD:475125	44/188 (23%)