Protein Alignment kar and Slc16a6

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_036012103.1
• Gene: Slc16a6 / 104681
• MGIID: 2144585
• Length: 559
• Species: Mus musculus
• Alignment Length: 525
• Identity: 104/525 - (19%)
• Similarity: 176/525 - (33%)
• Gaps: 175/525 - (33%)

  Fly    44 PSAPVQNGNGNANGTHIEAP-CCRDIHGKEPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSL 107
            |..|.:.|...:..|...:. |.|.....:.|||| ..|.|.||.|......:|.|.::||..:.
Mouse    72 PPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGG-WGWAVAVSFFFVEVFTYGIIKSFGVFFND 135

  Fly   108 LTDRLTKLGDPEASSKAALIGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFC 172
            |.|..     .|::||.:.|                                         .|.|
Mouse   136 LMDSF-----DESNSKISWI-----------------------------------------ISIC 154

  Fly   173 TENIGALYFTYGIMFGLGAALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLG 237
               :..|.||     |||...::.||:.||..||.:....|:...:.|.........|.:..|..
Mouse   155 ---VFVLTFT-----GLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKE 211

  Fly   238 SYGLEGTLRIMSLVSAFIILCSFVYKP--------------LHPPPE------------------ 270
            ..|...:|..:.|:...|::|..:.:|              |.|..|
Mouse   212 HIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSID 276

  Fly   271 -------PPKKKPGRSRINLFLRS------------------IINVEIWKRKRFVIWALCVPLAL 310
                   .||..|..:::....|:                  :::..:.|.|.|:.:||....|.
Mouse   277 SGVELTTSPKNVPSEAKMEQETRAEQQQTLVTAPKHSQMKAPLLDFSVLKEKSFICYALFGLFAT 341

  Fly   311 FGYFVPYVHMMQFVKTTFPGEDVNLPVMCIGITSGI------------------GRLIFGVIADM 357
            .|:|.|                 :|.::.:||:.||                  ||:..|.:.:.
Mouse   342 LGFFAP-----------------SLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNR 389

  Fly   358 PGVNRMYLQQLSLVSIGLVTLLLPLTNSYVILVSFT--------LVMGLFDGCFISLLG----PI 410
            ..:.::|::        |:.::| ||.|   |.:||        ::..:|.|..:..:|    |:
Mouse   390 EPIRKIYIE--------LICVIL-LTAS---LFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPM 442

  Fly   411 AYE--ICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLI 473
            ..|  :.|....:.|.|..:.:.||....|||:||::.|.:..|:...........|.:..|.|:
Mouse   443 LAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALV 507

  Fly   474 K-CVK 477
            : |.|
Mouse   508 RPCKK 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	92/482 (19%)
Slc16a6	XP_036012103.1	MFS_MCT7	108..508	CDD:340980	92/482 (19%)