DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kar and LOC103911912

DIOPT Version :9

Sequence 1:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	XP_021335977.1	Gene:	LOC103911912 / 103911912	-ID:	-	Length:	501	Species:	Danio rerio

Alignment Length:	486	Identity:	103/486 - (21%)
Similarity:	189/486 - (38%)	Gaps:	95/486 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 EPPDGGAR-----AWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALA 131
            |.||||..     .|:|.|:.||.....:|.|.::|:   .|.|.::...  |.:|:.:.|.::.
Zfish    19 EVPDGGVPLRPCWGWIVAVAFFLVEVFTYGVIKSFGI---FLKDLMSDFN--ETNSRVSWIISIC 78

  Fly   132 IGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYT 196
            :......:.::..|:::.|.:.....||.|.:.|.:.::| |.:|..:|.|.||:.|||..|.:.
Zfish    79 VFVMTFTAPLSTVLSNRFGFQPVVMFGGFLISLGTISTAF-TSSINQMYLTIGIVTGLGYCLTFL 142

  Fly   197 PTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFV 261
            ||:.||..||.|....|:...:.|.|.......|....|....|...|..::..:....|:|..:
Zfish   143 PTVTILSQYFSRRRSVVTAMASTGESFAIFAFAPAFTALKNYIGWRYTFVVIGTLQGITIICGAL 207

  Fly   262 YKPLHPPP------------------------------------------------EPPKKKPGR 278
            ..|:...|                                                ||.:..| :
Zfish   208 LHPIVIKPTSQTETEQKITYTLPGEQVQGFGSSGDSVVQSLEQEQGLKSGIELEEVEPVQVNP-K 271

  Fly   279 SRINLFLRSIINVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTTFPGED-VNLPVMCIGI 342
            .:.|.....::::.:.|...|:.::.....|..|:|.|.:::::...:.....| ....:..:.|
Zfish   272 QQDNTSKNRLLDLTVLKEGGFLCYSAFGLFATLGFFAPQLYVVELSASLGTERDKAAYMLSTMAI 336

  Fly   343 TSGIGRLIFGVIADMPGVNRMYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFDGCFIS-- 405
            :...|||..|.:.:...:.:::   :.|:.:.|:.|         :||.||:|.| |.|..:.
Zfish   337 SEIFGRLSIGWVMNCGCIRKIF---VLLICVSLMCL---------VLVLFTIVNG-FWGLVVCCV 388

  Fly   406 ----LLGPIAY---------EICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYTLPLI 457
                |||.||.         ::.|......|:|..:.:.|.....|||:.|::.|.|.:|:....
Zfish   389 LYGFLLGNIASTHIPMLAEDDVVGIQRMPLAVGVYVCIQSFAGLAGPPLGGVLVDITQNYSAAFY 453

  Fly   458 LAGLPPLLGSSLLFLIKCVK------EEENG 482
            .......||:..|.|::..|      ..:||
Zfish   454 SCAAGMGLGAIFLGLVRPAKTGHLCRRRKNG 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	91/441 (21%)
kar	NP_001189213.1	MFS_1	124..439	CDD:284993	72/378 (19%)
LOC103911912	XP_021335977.1	2A0111	21..468	CDD:331689	98/466 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920