Protein Alignment kar and slc16a5

DIOPT Version :10

• Sequence 1: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Sequence 2: XP_002940018.3
• Gene: slc16a5 / 100485544
• XenbaseID: XB-GENE-1008043
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 492
• Identity: 113/492 - (22%)
• Similarity: 206/492 - (41%)
• Gaps: 69/492 - (14%)

  Fly    72 EPPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTF 136
            |.|| |..||:|:.:..|..|:..||.:..|:.:   ||..|..  ..::::.:...::.:....
 Frog     2 ETPD-GPWAWVVLAAVMLTQGLSLGFPSCIGIFY---TDIQTSF--QASNTETSWFPSIIMAVLH 60

  Fly   137 LFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAI 201
            ....:...:.::.|.|:|...||:|...|::.|:| ::.|..||.:.|.:.|||....:...:.:
 Frog    61 AGGPLCTIMVERFGCRVTVMVGGLLCGVGMVTSAF-SQTIIHLYLSAGFVGGLGFCFCFQAGITV 124

  Fly   202 LGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKP-- 264
            ||:||.|.....:...:||:|:...:.|.....||.:.|..|:..:...|.....:|..:.:|
 Frog   125 LGYYFIRRRTLANSLASAGASIGMALWPLASQHLLETMGWRGSFLLFGGVLLNCCVCGAIMRPVR 189

  Fly   265 -LHP-------PPEPP---KKKPGRSRINLFLRSIINVE-IWKRKRFVIWALCVPLALFGYFVPY 317
             |.|       .||.|   |.|..::.....|:..:..: :::.:|:.|:||.|...:.|:.:|.
 Frog   190 SLEPAHEKEVLAPEEPNGIKHKGEKTEQGKGLQRYMAFDLLFRHRRYQIYALGVTWMVLGFVLPL 254

  Fly   318 VHMMQFVKTTFPGEDVN-----LPVMCIGITSGIGRLIFGVIADMPGVN--RMYLQQLSLVSIGL 375
            .:::.:..:    .|::     |.:..:|..:...|.:.|:::.....:  .|||..::::..||
 Frog   255 FYLVPYATS----NDIDEKKAALLLSLVGFMNIFMRPMAGLVSQQKVFHGRLMYLFSVAVILNGL 315

  Fly   376 VTLL------LPLTNSYVILVSFTLVMGLFDGCFI-SLLGPIAYEICGPSGATQAIGFLLGLSSI 433
            ..|:      .|...:|.:|.|.|:       .|| ||:..:..:..|......|.|....|.||
 Frog   316 SNLVCAIWVSFPALLTYCVLYSITM-------SFIGSLIFQVLMDTVGMKRFPGAFGLFTILESI 373

  Fly   434 PLTVGPPVAGMIFDSTNSYTLPLILAGLPPLLGSSLLFLIKCVKEEENGVSAPRAVVLANGDIEI 498
            .:..|||:||::.|.|..|.|....:.:  .:.||.||:                     |....
 Frog   374 TIMAGPPLAGLLVDITGQYGLVFYASSI--AVTSSGLFM---------------------GLASF 415

  Fly   499 AGNGHYRSAGTKSSAPLMGATNGINGSAPASPTIQSN 535
            |.:.....|...|..|.....|..||.|..||..|.:
 Frog   416 AVDRSEAKARRCSQRPTEATDNKDNGDAIYSPCKQED 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	97/421 (23%)
slc16a5	XP_002940018.3	MFS_MCT6	9..414	CDD:340983	98/444 (22%)