DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment kar and slc16a7

DIOPT Version :9

Sequence 1:	NP_001189213.1	Gene:	kar / 45883	FlyBaseID:	FBgn0001296	Length:	612	Species:	Drosophila melanogaster
Sequence 2:	NP_001106392.1	Gene:	slc16a7 / 100127205	XenbaseID:	XB-GENE-1008526	Length:	475	Species:	Xenopus tropicalis

Alignment Length:	464	Identity:	112/464 - (24%)
Similarity:	196/464 - (42%)	Gaps:	37/464 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 PPDGGARAWLVMVSAFLCNGIIFGFINTYGVIHSLLTDRLTKLGDPEASSKAALIGALAIGTTFL 137
            ||||| ..|:|:..:|:..|..:.|.....|....:.:...     .:.|:.|.|.::.:...:.
Frog    12 PPDGG-WGWVVVFGSFISIGFSYAFPKAITVFFKEIQEIFN-----TSYSEIAWISSIMLAVMYA 70

  Fly   138 FSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGAALAYTPTLAIL 202
            ...::..|.:|.|.|.....||||.:..::.:||| .::..||...|:|.|.|.|....|:|.|:
Frog    71 GGPISSILVNKYGSRPVVIGGGVLCSLAMISASFC-NSVMQLYICIGVMGGFGLAFNLQPSLTII 134

  Fly   203 GHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFIILCSFVYKPLHP 267
            |.||.:.....:|...|||.||...|.|....|...:|..|:..|:..:.....:...:.:|:.|
Frog   135 GKYFFKKRPIANGLAMAGSPVFLSTLAPLNQFLFNQFGWRGSFLILGGLLLNCCVAGSLMRPIGP 199

  Fly   268 PP------EPPKKKPGRSRINLFLRSI---INVEIWKRKRFVIWALCVPLALFGYFVPYVHMMQF 323
            .|      :.||......:.....:||   :::.::|.:.|:|:.....:...|:|.|.|.:..:
Frog   200 KPVKKDIEKAPKDDENHKKKESVCQSINKYLDLSLFKHRGFLIYLSGNVIMFIGFFAPIVFLAPY 264

  Fly   324 VKTTFPGEDVNLPVMCIGI---TSGIGRLIFGVIAD----MPGVNRMYLQQLSLVSIGLVTLLLP 381
            .|  ..|.|.......:.|   ...:.|...|::|:    .|.:  .|....:::..|:..||.|
Frog   265 AK--HMGIDQYSSAFLLSILAFVDMVARPTMGMVANTRFIRPRI--QYFFSFAILYNGVCHLLCP 325

  Fly   382 LTNSYVILVSFTLVMGLFDGCFISLLGPIAYEICGPSGATQAIGFLLGLSSIPLTVGPPVAGMIF 446
            |.|.|..||.:.:..|...|...|:|.....:|.|.:..:.|:|....:...|:.:|||:.|.:.
Frog   326 LANDYTGLVIYAVFFGFAFGMVSSVLFETLMDIVGAARFSSAVGLTTIVECCPVLIGPPLGGFLV 390

  Fly   447 DSTNSYTLPLILAGLPPLLGSSLLFL-----IKCVKEEENGVSAPRAVVLANGDI---EIAGNGH 503
            |.|.:|.....:.|:..::.|..||:     .:.:.:|:...||..  :....|:   |...|..
Frog   391 DVTGNYKYMYFVCGVIVIIASIWLFIGNAINYRMLAKEKMATSAKN--IDEKTDLKETEPLNNPE 453

  Fly   504 YRSAGTKSS 512
            .....||||
Frog   454 TLDVATKSS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
kar	NP_001189213.1	MFS	81..459	CDD:119392	93/393 (24%)
kar	NP_001189213.1	MFS_1	124..439	CDD:284993	79/330 (24%)
slc16a7	NP_001106392.1	2A0113	10..447	CDD:273325	106/447 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920