Protein Alignment Ldh and MDH2

DIOPT Version :9

• Sequence 1: NP_001261474.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_014515.2
• Gene: MDH2 / 853994
• SGDID: S000005486
• Length: 377
• Species: Saccharomyces cerevisiae
• Alignment Length: 388
• Identity: 91/388 - (23%)
• Similarity: 152/388 - (39%)
• Gaps: 110/388 - (28%)

  Fly    22 KVTIVG-IGQVGMASAFSILAQ----------NVSK-EVCLIDVCADKLQGELMDLQHGSNFLKN 74
            |:.|:| .|.:|.:.:..:.||          :|:. .:.|.||..:.:.|...||.|    :..
Yeast    15 KIAILGAAGGIGQSLSLLLKAQLQYQLKESNRSVTHIHLALYDVNQEAINGVTADLSH----IDT 75

  Fly    75 PQITASTDFAASA------NSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYS--PDT 131
            | |:.|:...|..      |:.:.::.|||.:|.|.:|..|...|..|:..:...:.|..  ...
Yeast    76 P-ISVSSHSPAGGIENCLHNASIVVIPAGVPRKPGMTRDDLFNVNAGIISQLGDSIAECCDLSKV 139

  Fly   132 ILLMVSNPVDIMTYVAWKLSGLPKN-----------RVIGSGTNLD---SSRFRFLMSQRLGVAP 182
            .:|::||||:.:..|  .:|.:.||           |::|. |.||   :|.|...::...|:.|
Yeast   140 FVLVISNPVNSLVPV--MVSNILKNHPQSRNSGIERRIMGV-TKLDIVRASTFLREINIESGLTP 201

  Fly   183 ---TSCHGWIIGEH-GDSSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIK 243
               :.....:||.| |::.:|::|..|.    |..||      ||..|:  |..:|.....||:|
Yeast   202 RVNSMPDVPVIGGHSGETIIPLFSQSNF----LSRLN------EDQLKY--LIHRVQYGGDEVVK 254

  Fly   244 LKGYTSWAIGLSTASLASAILRNTSSVAAVSTSVLGE----HG---------------------- 282
            .|.    ..|.:|.|:|.|   ....|....:.:||.    ||
Yeast   255 AKN----GKGSATLSMAHA---GYKCVVQFVSLLLGNIEQIHGTYYVPLKDANNFPIAPGADQLL 312

  Fly   283 --IDKDVFLSLPCVLNANGVTSVVKQI-----------LTPTEVEQLQKSANIMSDVQAGLKF 332
              :|...:.::|..:...||:.|...|           :.|..|.||:|      ::..||:|
Yeast   313 PLVDGADYFAIPLTITTKGVSYVDYDIVNRMNDMERNQMLPICVSQLKK------NIDKGLEF 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_001261474.1	LDH_1	18..329	CDD:133429	88/383 (23%)
MDH2	NP_014515.2	MDH_euk_gproteo	15..372	CDD:130833	91/388 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810