Protein Alignment Ldh and MDH1

DIOPT Version :9

• Sequence 1: NP_001261474.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_012838.1
• Gene: MDH1 / 853777
• SGDID: S000001568
• Length: 334
• Species: Saccharomyces cerevisiae
• Alignment Length: 365
• Identity: 90/365 - (24%)
• Similarity: 161/365 - (44%)
• Gaps: 75/365 - (20%)

  Fly     8 LLAQVAEVLPSS----GHKVTIVGIGQVGMASAFSILAQNVSK--EVCLIDVCADKLQGELMDLQ 66
            :|::||:...||    .:|||::|.|. |:....|:|.:...|  ::.|.|:...|  |...||.
Yeast     1 MLSRVAKRAFSSTVANPYKVTVLGAGG-GIGQPLSLLLKLNHKVTDLRLYDLKGAK--GVATDLS 62

  Fly    67 H----------------G-SNFLKNPQITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNT 114
            |                | :|.||:      ||        :.::.|||.:|.|.:|..|...|.
Yeast    63 HIPTNSVVKGFTPEEPDGLNNALKD------TD--------MVLIPAGVPRKPGMTRDDLFAINA 113

  Fly   115 DILKNIIPKLVEYSPDTILLMVSNPVD----IMTYVAWKLSGLPKNRVIGSGTNLDSSRFRFLMS 175
            .|::::.....|.:|:..:|::||||:    |:..|. |..|:...:.:...|.|||.|....:|
Yeast   114 SIVRDLAAATAESAPNAAILVISNPVNSTVPIVAQVL-KNKGVYNPKKLFGVTTLDSIRAARFIS 177

  Fly   176 QRLGVAPTSCHGWIIGEH-GDSSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAY 239
            :.....||.....:||.| |.:.:|:.|..|         :.::    ..:|.:||..::.....
Yeast   178 EVENTDPTQERVNVIGGHSGITIIPLISQTN---------HKLM----SDDKRHELIHRIQFGGD 229

  Fly   240 EVIKLK---GYTSWAIGLSTASLASAIL------RNTSSVAAVSTSVLGEHGIDKDVFLSLPCVL 295
            ||:|.|   |..:.::..:.|..|:|:|      |:....:.|.:.:....||:   |.:.|..|
Yeast   230 EVVKAKNGAGSATLSMAHAGAKFANAVLSGFKGERDVIEPSFVDSPLFKSEGIE---FFASPVTL 291

  Fly   296 NANGVTSV--VKQILTPTEVEQLQK-SANIMSDVQAGLKF 332
            ..:|:..:  :.: |:..|.|.||| ...:..:::.|:.|
Yeast   292 GPDGIEKIHPIGE-LSSEEEEMLQKCKETLKKNIEKGVNF 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_001261474.1	LDH_1	18..329	CDD:133429	85/350 (24%)
MDH1	NP_012838.1	MDH_glyoxysomal_mitochondrial	18..331	CDD:133422	85/348 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740