Protein Alignment Ldh and MDH3

DIOPT Version :9

• Sequence 1: NP_001261474.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_010205.1
• Gene: MDH3 / 851481
• SGDID: S000002236
• Length: 343
• Species: Saccharomyces cerevisiae
• Alignment Length: 364
• Identity: 85/364 - (23%)
• Similarity: 164/364 - (45%)
• Gaps: 83/364 - (22%)

  Fly    22 KVTIVGI-GQVGMASAFSILAQNVSKEVCLIDVCADKLQGELMDLQH----------GSNFLKNP 75
            ||.|:|. |.||...:..:.......|:.|.|:.|  .:|...||.|          ..:.::|
Yeast     3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSIEN- 64

  Fly    76 QITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPDTILLMVSNPV 140
                     ..:|:::.::.|||.:|.|.:|..|.:.|..|:|:::..:.:::|:..:|::||||
Yeast    65 ---------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120

  Fly   141 DIMTYVA----WKLSGLPKNRVIGSGTNLDSSR-------FRFLMSQRLGVA--PTSCHG--WII 190
            :.:..:|    .|:.......|:|. ||||..|       :..|.:.::|..  .|:.|.  .:|
Yeast   121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI 184

  Fly   191 GEH-GDSSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIKLK---GYTSWA 251
            |.| |::.:|:.:..::    :.:|        |.:..:.:|: |.....|::|.|   |..:.:
Yeast   185 GGHSGETIIPIITDKSL----VFQL--------DKQYEHFIHR-VQFGGDEIVKAKQGAGSATLS 236

  Fly   252 IGLSTASLASAILRN-------TSSVAAV-----------STSVLGEHGIDKDVFLSLPCVLNAN 298
            :..:.|..|..:||:       |.|::|.           :..::|::.|:   :.|||.||...
Yeast   237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE---YFSLPIVLRNG 298

  Fly   299 GVTSV---VKQILTPTEVEQLQKSA--NIMSDVQAGLKF 332
            .|.|:   |.:.|:|.| |||..:|  .:..:::.|..|
Yeast   299 SVVSIDTSVLEKLSPRE-EQLVNTAVKELRKNIEKGKSF 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_001261474.1	LDH_1	18..329	CDD:133429	83/359 (23%)
MDH3	NP_010205.1	MDH_euk_gproteo	3..339	CDD:130833	85/364 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344311
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100601
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.640