Protein Alignment Ldh and mdh1b

DIOPT Version :9

• Sequence 1: NP_001261474.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: XP_009303919.1
• Gene: mdh1b / 767794
• ZFINID: ZDB-GENE-060929-384
• Length: 471
• Species: Danio rerio
• Alignment Length: 285
• Identity: 60/285 - (21%)
• Similarity: 90/285 - (31%)
• Gaps: 111/285 - (38%)

  Fly    60 GELMDLQHGSNFLKNPQITASTDFAASANSRLCI----------VTAGVRQKEGESRLSLVQRNT 114
            |:|::    :|..|:.::..:.||..:....|.|          ..|...|.|.|:|..|.|:
Zfish   241 GQLIE----TNAQKDVRVLVAGDFFINMKCSLLIENAPSIDPRNFVAMTTQLEYEARTQLAQK-- 299

  Fly   115 DILKNIIPKLVEYSPDTILLMVSNPVDIMTYVAW-KLSGLPKNRVIGSGTNLDSSR---FRFLMS 175
                               |.|... ||...:.| .:||         ..::|..|   ||:
Zfish   300 -------------------LSVKTS-DITNVIVWGNISG---------SFHIDLQRAKVFRY--- 332

  Fly   176 QRLGVAPTSCHGWIIGEHGDSS-----VPVWSGVNIAGVRLRELNPILGTGEDPEKW------NE 229
                      .|.|.|..|.|.     :..|                        ||      :.
Zfish   333 ----------DGAIRGPDGFSQHVMEMIYDW------------------------KWLKTDFRSL 363

  Fly   230 LHKQVVDSAYEVIKLKGYTSWAIGLSTASLASAILR---NTSSVAAV-STSVL--GEHGIDKDVF 288
            |||...       .:...|:.|..:||.:...|||:   |..|...| |..||  |:.||...:.
Zfish   364 LHKHRA-------TISSKTNKATAISTTNAILAILKAWNNAESPEEVFSLGVLSTGQFGIPAGLV 421

  Fly   289 LSLPCVLNANGVTSVVKQILTPTEV 313
            .|:| |...:|..||...::...|:
Zfish   422 FSMP-VSFTDGHWSVRSDVIVTDEL 445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_001261474.1	LDH_1	18..329	CDD:133429	60/285 (21%)
mdh1b	XP_009303919.1	NADB_Rossmann	9..463	CDD:304358	60/285 (21%)
		MalateDH-SF1	131..463	CDD:130820	60/285 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810