Protein Alignment Ldh and mdh1aa

DIOPT Version :10

• Sequence 1: NP_476581.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001303854.1
• Gene: mdh1aa / 399662
• ZFINID: ZDB-GENE-040204-1
• Length: 354
• Species: Danio rerio
• Alignment Length: 364
• Identity: 74/364 - (20%)
• Similarity: 134/364 - (36%)
• Gaps: 87/364 - (23%)

  Fly    22 KVTIVG-IGQVGMASAFSILAQNV-SKEVCLIDVCAD------KLQGELMDLQHGSNFLKNPQIT 78
            :|.:.| .||:..:..:||...:| .|:..:|.|..|      .|.|.:|:||..:..|....|.
Zfish     6 RVLVTGAAGQIAYSLLYSIAKGDVFGKDQPIILVLLDITPMLPVLDGVVMELQDCALPLLREVIP 70

  Fly    79 ASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPDTI-LLMVSNPVDI 142
            .........:....|:...:.:|||..|..|::.|..|.|.....|.:|:..|: :|:|.||.:.
Zfish    71 TDKVEVGFKDLDAAILVGSMPRKEGMERKDLLKANVAIFKTQGEALEKYAKKTVKVLVVGNPANT 135

  Fly   143 MTYVAWKLS-GLPKNRVIGSGTNLDSSRFRFLMSQRLGVAPTSCHGWII-GEHGDSSVPVWSGVN 205
            ...:|.|.: .:||.. ....|.||.:|.|..::.|:||...|.....| |.|..:..|
Zfish   136 NCLIASKSAPSIPKEN-FSCLTRLDHNRARSQVAMRVGVPSDSVKNVTIWGNHSSTQYP------ 193

  Fly   206 IAGVRLRELNPILGTGEDPEKWNELHKQVVD------SAYEVIKLKGYTSWAIG--LSTASLASA 262
                                   ::|..:|.      :|::.:..:   ||..|  :||.....|
Zfish   194 -----------------------DVHHAIVTRNGKEIAAFDAVNDE---SWLKGDFISTVQQRGA 232

  Fly   263 IL---RNTSSVAAVSTSVL------------GE------------HGIDKDVFLSLPC------- 293
            .:   |..||..:.:.::.            ||            :|:..|:..|.|.
Zfish   233 AVIKARKLSSAMSAAKAICDHMRDIWFGTPDGEWVSMGIYSSGNSYGVPDDLMYSFPVKIKNKSW 297

  Fly   294 -VLNANGVTSVVKQILTPTEVEQLQKSANIMSDVQAGLK 331
             |::...:....:..:..|..|.:::....::.:.|.|:
Zfish   298 KVVDGLSINDFSRGKMDATAAELVEERDTALTFLSAXLQ 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_476581.1	LDH_1	18..329	CDD:133429	72/360 (20%)
mdh1aa	NP_001303854.1	MDH_cytoplasmic_cytosolic	3..328	CDD:133421	72/354 (20%)
		PTS1	352..354