Protein Alignment Ldh and Mdh2

DIOPT Version :10

• Sequence 1: NP_476581.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: XP_321163.4
• Gene: Mdh2 / 1281223
• VectorBaseID: AGAMI1_003251
• Length: 337
• Species: Anopheles gambiae
• Alignment Length: 345
• Identity: 89/345 - (25%)
• Similarity: 143/345 - (41%)
• Gaps: 71/345 - (20%)

  Fly    22 KVTIVGIGQVGMASAFSILAQN--VSKEVCLIDVCADKLQGELMDLQH--------GSNFLKNPQ 76
            ||.:.| ...|:....|:|.:|  :..|:.|.|:.  ...|...||.|        |.|..:|.:
Mosquito    26 KVAVCG-ASGGIGQPLSLLLKNSPLVTELSLYDIV--HTPGVAADLSHIETQSKVTGYNGPENLE 87

  Fly    77 ITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPDTILLMVSNPVD 141
                   .|...:.:.|:.|||.:|.|.:|..|...|..|::::.....:..|..::.::||||:
Mosquito    88 -------KALKGADIVIIPAGVPRKPGMTRDDLFNTNASIVRDLAAGCAKACPKALIGIISNPVN 145

  Fly   142 IMTYVA----WKLSGLPKNRVIGSGTNLDSSRFRFLMSQRLGVAPTSCHGWIIGEHGDSSVPVWS 202
            ....:|    .|...|...||.|..| ||..|....:.:..||.|......:||.|        |
Mosquito   146 STVPIACDTLQKAGVLDPRRVFGVST-LDIVRANTFVGEAAGVDPQKMSVPVIGGH--------S 201

  Fly   203 GVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIKLK---GYTSWAIGLSTASLASAIL 264
            ||.|..| |.:..|  |.....:|...|.:::.::..||:|.|   |..:.::..:.|..|.|:.
Mosquito   202 GVTIIPV-LSQTKP--GVNFPQDKITALTERIQEAGTEVVKAKAGAGSATLSMAYAGARFALALA 263

  Fly   265 R------NTSSVAAVSTSV-----------LGEHGIDKDVFLSLPCVLNANGVTSVVKQILTPTE 312
            |      |....|.|.:.|           ||::|::|:  |.|| .|||      .:|.|....
Mosquito   264 RAMNGEQNVIECAYVRSDVTESKYFATPLLLGKNGLEKN--LGLP-KLNA------YEQELLKKA 319

  Fly   313 VEQLQKSANIMSDVQAGLKF 332
            :.:|:|      ::|.|.:|
Mosquito   320 IPELKK------NIQKGEEF 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_476581.1	LDH_1	18..329	CDD:133429	87/340 (26%)
Mdh2	XP_321163.4	MDH_glyoxysomal_mitochondrial	25..334	CDD:133422	89/345 (26%)