Protein Alignment Ldh and Ldhal6b

DIOPT Version :9

• Sequence 1: NP_001261474.1
• Gene: Ldh / 45880
• FlyBaseID: FBgn0001258
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_780558.1
• Gene: Ldhal6b / 106557
• MGIID: 2146830
• Length: 382
• Species: Mus musculus
• Alignment Length: 332
• Identity: 175/332 - (52%)
• Similarity: 247/332 - (74%)
• Gaps: 0/332 - (0%)

  Fly     1 MAAIKDSLLAQVAEVLPSSGHKVTIVGIGQVGMASAFSILAQNVSKEVCLIDVCADKLQGELMDL 65
            ||.:|..|:..::...|...:||:|||.|.||||.|..|:|:.::.|:.|:|...:|::||.|||
Mouse    51 MATVKGELIQHISSEEPVLHNKVSIVGTGSVGMACAIGIIAKGLTDELALVDNNEEKMKGETMDL 115

  Fly    66 QHGSNFLKNPQITASTDFAASANSRLCIVTAGVRQKEGESRLSLVQRNTDILKNIIPKLVEYSPD 130
            ||||.|:|.|.|..|.||..:|||.:.|:|||.||::.|:||:|||||..|.|.::.:::::||.
Mouse   116 QHGSVFMKMPNIVCSKDFRVTANSEVVIITAGARQEKNETRLNLVQRNVTIFKAMVAEIIKHSPR 180

  Fly   131 TILLMVSNPVDIMTYVAWKLSGLPKNRVIGSGTNLDSSRFRFLMSQRLGVAPTSCHGWIIGEHGD 195
            ..:::|||||||:|:|.|||||.||||:||||.|||::|||:::.||||:...|||||::|||||
Mouse   181 CKIIVVSNPVDILTFVTWKLSGFPKNRIIGSGCNLDTARFRYMLGQRLGIHSESCHGWVLGEHGD 245

  Fly   196 SSVPVWSGVNIAGVRLRELNPILGTGEDPEKWNELHKQVVDSAYEVIKLKGYTSWAIGLSTASLA 260
            ||||||||||||||.|||||..:||.:|||||.::||:|:.|||.:||:|||||||||||...:|
Mouse   246 SSVPVWSGVNIAGVPLRELNSAIGTSKDPEKWGDVHKEVIASAYNIIKMKGYTSWAIGLSVTDIA 310

  Fly   261 SAILRNTSSVAAVSTSVLGEHGIDKDVFLSLPCVLNANGVTSVVKQILTPTEVEQLQKSANIMSD 325
            .:||:|......|:|.:.|.:||.::||||:||:|..:|::.::|..|:|||..|:.|||..:..
Mouse   311 ESILKNLRKTHPVTTKIQGLYGIKEEVFLSVPCILGESGISDIIKVKLSPTEEAQMVKSAETIWK 375

  Fly   326 VQAGLKF 332
            :|..:||
Mouse   376 IQKDIKF 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ldh	NP_001261474.1	LDH_1	18..329	CDD:133429	168/310 (54%)
Ldhal6b	NP_780558.1	LDH_1	70..379	CDD:133429	168/308 (55%)
		L-LDH-NAD	75..375	CDD:273796	165/299 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	223	1.000	Domainoid score	I2560
eggNOG	1	0.900	-	-		E1_COG0039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	426	1.000	Inparanoid score	I1737
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59943
OrthoDB	1	1.010	-	-		D1204514at2759
OrthoFinder	1	1.000	-	-		FOG0001004
OrthoInspector	1	1.000	-	-		otm42523
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43128
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X661
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.980